Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20249092 | 0.82 | PTGDR2 (0.43) | PTGDR2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL2553005 | 0.81 | KDM4E (0.61) | PTGDR2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL7365741 | 0.80 | PTGDR2 (0.60) | PTGDR2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL29955221 | 0.79 | PTGDR2 (0.62) | PTGDR2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL29951938 | 0.78 | PTGDR2 (0.60) | PTGDR2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL15332808 | 0.77 | PTGDR2 (0.59) | PTGDR2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL2109475 | 0.76 | PTGDR2 (0.66) | PTGDR2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL2560324 | 0.76 | PTGDR2 (0.57) | PTGDR2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL29951271 | 0.76 | PTGDR2 (0.57) | PTGDR2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL15331806 | 0.76 | PTGDR2 (0.57) | PTGDR2NPC1NFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018104962-A1 | HEMIAMINAL-TAG FOR PROTEIN LABELING AND PURIFICATION | Indian Institute Of Science Education And Research Bhopal (IN) | 2018-06-14 | — | — | WO | disclosed |