Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 5/20 | 0.35 |
| ▸ | FNTB | P49356 | 4/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | NRAS | P01111 | 1/20 | 0.33 |
| ▸ | HRAS | P01112 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CCR9 | P51686 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20249319 | 0.84 | DRD3 (0.35) | LMNATSHRDRD3KCNH2FNTA | |
| SCHEMBL20255395 | 0.84 | DRD3 (0.50) | ALDH1A1DRD3KCNH2FNTAFNTB | |
| SCHEMBL20249300 | 0.82 | PIK3CD (0.43) | DRD3KCNH2L3MBTL1HRH3PARP1 | |
| SCHEMBL20249309 | 0.82 | GAA (0.37) | ALDH1A1LMNATSHRDRD3KCNH2 | |
| SCHEMBL20249326 | 0.82 | AR (0.36) | LMNATSHRDRD3KCNH2AR | |
| SCHEMBL20249369 | 0.80 | ALDH1A1 (0.38) | ALDH1A1LMNATSHRDRD3KCNH2 | |
| SCHEMBL20249342 | 0.80 | PARP1 (0.35) | DRD3KCNH2DRD2PPARDPPARA | |
| SCHEMBL20249115 | 0.78 | SLC6A2 (0.42) | LMNATSHRDRD3KCNH2L3MBTL1 | |
| SCHEMBL20249402 | 0.78 | TLR8 (0.37) | ALDH1A1LMNATSHRDRD3KCNH2 | |
| SCHEMBL20249390 | 0.78 | IDH1 (0.33) | HRH3TP53DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180161329-A1 | PYRIDO[3,4-D]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TEIJIN PHARMA LIMITED (JP) | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180161329-A1 | PYRIDO[3,4-D]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | CDK4, CDK6, CDK16 | ALDH1A1 944/4885LMNA 3947/4885TSHR 2977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.