SCHEMBL20249648

SCHEMBL20249648

Cc1c2c(-c3ccccc3)nc3cc(-c4ccccn4)ccc3c2c(C)c2c(-c3ccccc3)nc3ccccc3c12

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
DHODH Q02127 6/20 0.44
METAP1 P53582 3/20 0.41
TSHR P16473 2/20 0.40
PDE10A Q9Y233 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
RET P07949 1/20 0.40
RIPK1 Q13546 1/20 0.40
RIPK3 Q9Y572 1/20 0.40
PKMYT1 Q99640 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TOP1 P11387 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20245248 0.95 DHODH (0.43) KDM4ENPC1DHODHMETAP1TSHR
SCHEMBL20245040 0.95 DHODH (0.45) KDM4ENPC1DHODHMETAP1TSHR
SCHEMBL20245081 0.95 KDM4E (0.44) KDM4ENPC1DHODHTSHRTDP1
SCHEMBL20245075 0.93 MAPK1 (0.41) KDM4ENPC1DHODHMETAP1TSHR
SCHEMBL20249689 0.91 DHODH (0.49) KDM4ENPC1DHODHMETAP1TSHR
SCHEMBL20249640 0.90 DHODH (0.39) KDM4ENPC1DHODHMETAP1TSHR
SCHEMBL20249667 0.90 KDM4E (0.47) KDM4ENPC1DHODHMETAP1TSHR
SCHEMBL20249611 0.89 KDM4E (0.39) KDM4ENPC1DHODHMETAP1TSHR
SCHEMBL20249635 0.89 PIK3CD (0.41) KDM4ENPC1DHODHTOP1
SCHEMBL20249614 0.88 KDM4E (0.38) KDM4ENPC1DHODHMETAP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3333168-B1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2022-01-26 EP disclosed
US-10693083-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-06-23 US disclosed
US-20180166635-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-14 US disclosed
US-20180166635-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180166635-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 KDM4E 3511/4885NPC1 1192/4885DHODH 1907/4885
US-10693083-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 KDM4E 3511/4885NPC1 1192/4885DHODH 1907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.