SCHEMBL20249688

SCHEMBL20249688

Cc1c2c(-c3ccccc3)nc3cc(-c4cccc(S(=O)(=O)c5ccccc5)c4)ccc3c2c(C)c2c(-c3ccccc3)nc3ccccc3c12

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 6/20 0.42
NR1H3 Q13133 1/20 0.42
DHODH Q02127 3/20 0.41
TSHR P16473 1/20 0.40
PDE10A Q9Y233 1/20 0.40
TARS1 P26639 2/20 0.39
TDP1 Q9NUW8 1/20 0.38
TTK P33981 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20249650 0.94 DHODH (0.45) NR1H2NR1H3DHODHTSHRPDE10A
SCHEMBL17300244 0.87 TTK (0.39) NR1H2NR1H3TARS1TDP1TTK
SCHEMBL20249645 0.85 DHODH (0.51) DHODHTSHRPDE10ATDP1
SCHEMBL17300239 0.83 TTK (0.39) NR1H2NR1H3DHODHTDP1TTK
SCHEMBL20249610 0.82 DHODH (0.46) DHODHTSHRPDE10ATDP1
SCHEMBL17300245 0.81 TDP1 (0.41) DHODHTDP1TTKCA12CA1
SCHEMBL20245165 0.81 MEN1 (0.45) DHODHTSHRPDE10ATDP1
SCHEMBL20249722 0.81 DHODH (0.42) DHODHTSHRPDE10ATDP1
SCHEMBL20245417 0.81 DHODH (0.42) DHODHTSHRPDE10ATDP1
SCHEMBL20249691 0.80 DHODH (0.47) DHODHTSHRPDE10ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3333168-B1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2022-01-26 EP disclosed
US-10693083-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-06-23 US disclosed
US-20180166635-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-14 US disclosed
US-20180166635-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180166635-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 NR1H2 487/4885NR1H3 563/4885DHODH 1907/4885
US-10693083-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 NR1H2 487/4885NR1H3 563/4885DHODH 1907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.