SCHEMBL202497

SCHEMBL202497

NC(=O)c1cccc(OCc2cccc(O)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
F2 P00734 8/20 0.61
NR4A2 P43354 4/20 0.59
PARP1 P09874 1/20 0.59
MAOB P27338 6/20 0.56
PARP10 Q53GL7 2/20 0.56
PARP15 Q460N3 1/20 0.56
PARP14 Q460N5 1/20 0.56
MAOA P21397 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1387246 0.88 NR4A2 (0.77) F2NR4A2MAOBPARP10
Hydrochloric Acid SCHEMBL27603151 0.86 NR4A2 (0.74) F2NR4A2MAOBPARP10
SCHEMBL15452539 0.85 NR4A2 (0.77) F2NR4A2PARP1MAOBMAOA
SCHEMBL201347 0.85 MAOB (0.77) F2NR4A2PARP1MAOBPARP10
SCHEMBL202474 0.85 PARP15 (0.77) F2NR4A2PARP1MAOBPARP10
SCHEMBL19980221 0.84 F10 (0.72) F2NR4A2MAOBPARP10PARP15
SCHEMBL201369 0.83 MAOB (0.58) F2NR4A2PARP1MAOBPARP10
SCHEMBL4638462 0.82 F2 (0.68) F2NR4A2MAOB
SCHEMBL2654709 0.82 MRGPRX4 (0.71) NR4A2MAOBMAOA
SCHEMBL4639564 0.82 MRGPRX4 (0.61) F2NR4A2MAOBPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 US disclosed
US-20130072520-A2 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2013-03-21 US disclosed
US-20130072520-A2 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2013-03-21 US disclosed
US-20130072520-A2 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2013-03-21 US disclosed
US-20120122918-A1 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2012-05-17 US disclosed
US-8088791-B2 Antibacterial agents Biots Scientific Management Pty Ltd (AU) 2012-01-03 US disclosed
US-8088791-B2 Antibacterial agents Biots Scientific Management Pty Ltd (AU) 2012-01-03 US disclosed
US-8088791-B2 Antibacterial agents Biots Scientific Management Pty Ltd (AU) 2012-01-03 US disclosed
EP-1996180-B1 BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS BIOTA EUROPE LTD (GB) 2011-08-03 EP disclosed
EP-1996180-B1 BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS BIOTA EUROPE LTD (GB) 2011-08-03 EP disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed
WO-2007107758-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2007-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120122918-A1 ANTIBACTERIAL AGENTS ALK, ROS1, ARG1 F2 3659/4885NR4A2 1464/4885PARP1 1024/4885
US-20130072520-A2 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 F2 2751/4885NR4A2 1340/4885PARP1 1034/4885
US-20150191420-A1 ANTIBACTERIAL AGENTS ALK, ARG1, ROS1 F2 3895/4885NR4A2 957/4885PARP1 1040/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 F2 2751/4885NR4A2 1340/4885PARP1 1034/4885
US-20100173933-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 F2 2751/4885NR4A2 1340/4885PARP1 1034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.