Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20249876 | 0.87 | PDK2 (0.38) | PDK2LMNAAKR1A1AKR1B1ESR1 | |
| SCHEMBL20249883 | 0.86 | PDK2 (0.35) | PDK2LMNAKIF11MEN1KMT2A | |
| SCHEMBL20249884 | 0.86 | PDK2 (0.37) | PDK2LMNAAKR1A1AKR1B1MEN1 | |
| SCHEMBL20249889 | 0.81 | PDK2 (0.43) | PDK2LMNAAKR1A1AKR1B1KCNN4 | |
| SCHEMBL20256603 | 0.81 | KCNA5 (0.39) | PDK2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL15213577 | 0.79 | PDK2 (0.50) | PDK2AKR1A1AKR1B1MMP2MMP9 | |
| SCHEMBL3799675 | 0.78 | LMNA (0.43) | LMNAESR1MEN1KMT2AKDM4E | |
| SCHEMBL16544664 | 0.77 | PDK2 (0.43) | PDK2AKR1A1AKR1B1MAPTMMP2 | |
| SCHEMBL17523190 | 0.76 | LMNA (0.39) | LMNAESR1MEN1KMT2AKDM4E | |
| SCHEMBL20249877 | 0.76 | PDK2 (0.38) | PDK2LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180166639-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-06-14 | — | — | US | disclosed |
| US-20180166639-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180166639-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | RCC1, CCNA1, CTCF | PDK2 2677/4885LMNA 1158/4885AKR1A1 2256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.