Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.40 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20224015 | 0.77 | ACHE (0.67) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Bromide SCHEMBL50527 | 0.77 | CHRM2 (0.50) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Iodide SCHEMBL9671893 | 0.77 | KCNH2 (0.62) | KCNH2CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL53656 | 0.76 | HTT (0.57) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL13527279 | 0.75 | KMT2A (0.63) | KCNH2CHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL9672440 | 0.75 | KCNH2 (0.66) | KCNH2CHRM2CHRM5CHRM1CHRM3 | |
| Iodide SCHEMBL9671227 | 0.75 | KCNH2 (0.66) | KCNH2CHRM2CHRM5CHRM1CHRM3 | |
| Iodide SCHEMBL9671951 | 0.75 | KCNH2 (0.66) | KCNH2CHRM2CHRM5CHRM1CHRM3 | |
| Iodide SCHEMBL9671839 | 0.75 | KCNH2 (0.66) | KCNH2CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL5299708 | 0.75 | KMT2A (0.63) | KCNH2CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180161364-A1 | CATIONIC COMPOUNDS AND THEIR USE AS ANTIMYCOTIC AND ANTIMICROBIAL AGENTS | CHIROBLOCK GMBH (DE) | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180161364-A1 | CATIONIC COMPOUNDS AND THEIR USE AS ANTIMYCOTIC AND ANTIMICROBIAL AGENTS | MFN2, OTC, DPM1 | KCNH2 638/4885CHRM2 3866/4885CHRM4 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.