SCHEMBL2025317

SCHEMBL2025317

CCc1ccc(CC(C)c2ccc(O)c(C(C)Cc3ccc(CC)c(CC)c3CC)c2C(C)Cc2ccc(CC)c(CC)c2CC)c(CC)c1CC

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
TSHR P16473 1/20 0.32
RORC P51449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2020837 0.91 GABRA1 (0.37) ALOX15ALOX12TSHR
SCHEMBL1840008 0.87 TSHR (0.41) ALOX15ALOX12TSHR
SCHEMBL2018619 0.83 TSHR (0.40) ALOX15ALOX12TSHRRORC
SCHEMBL2022146 0.82 PRKCI (0.35) TSHR
SCHEMBL1954274 0.82 ALOX15 (0.34) ALOX15ALOX12TSHRRORC
SCHEMBL1841288 0.81 TSHR (0.41) ALOX15ALOX12TSHR
SCHEMBL2021093 0.80 TYR (0.39) ALOX15TSHR
SCHEMBL2022485 0.78 TSHR (0.58) ALOX15ALOX12TSHR
SCHEMBL2023305 0.77 GABRA1 (0.33) TSHR
SCHEMBL1954633 0.77 GABRA1 (0.37) ALOX15ALOX12TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110160476-A1 N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110160476-A1 N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester ALKBH3, CPS1, APEH ALOX15 464/4885ALOX12 470/4885TSHR 2998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.