Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465681 | 0.74 | PIM1 (0.49) | PIM1CYP3A4KDM4EGAAMAPT | |
| SCHEMBL2023742 | 0.73 | PIM1 (0.40) | PIM1CYP3A4KDM4EGAAMAPT | |
| SCHEMBL3994781 | 0.70 | PIM1 (0.51) | PIM1KDM4EGAAMAPTACHE | |
| SCHEMBL3164738 | 0.69 | AKT1 (0.40) | PIM1KDM4EGAAMAPTRAB9A | |
| SCHEMBL7538049 | 0.68 | PIM1 (0.53) | PIM1KDM4EGAAMAPTACHE | |
| SCHEMBL28125896 | 0.67 | KDM4E (0.50) | PIM1KDM4EGAAMAPTACHE | |
| SCHEMBL24194106 | 0.66 | PIM1 (0.44) | PIM1CYP3A4KDM4EGAAMAPT | |
| SCHEMBL31268722 | 0.65 | PIM1 (0.50) | PIM1KDM4EGAAMAPTACHE | |
| SCHEMBL8949861 | 0.65 | PIM1 (0.50) | PIM1KDM4EGAAMAPTACHE | |
| SCHEMBL12723861 | 0.65 | ACHE (0.57) | PIM1KDM4EGAAACHETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073151-A2 | METHOD FOR THE TWO-STEP DYEING OF KERATIN FIBRES, BY APPLICATION OF A COMPOSITION COMPRISING A NAPHTALENE DERIVATIVE, THEN ALKALINE TREATMENT. | L'OREAL (FR) | 2011-06-23 | — | — | WO | claimed |
| EP-0850635-B1 | Process for oxydative dyeing of keratinic fibers in two steps with a manganese salt or a manganese complex and a 1-naphtol substituted in position 4 and a dyeing set | OREAL (FR) | 1999-07-14 | — | — | EP | claimed |
| EP-0850635-A1 | Process for oxydative dyeing of keratinic fibers in two steps with a manganese salt or a manganese complex and a 1-naphtol substituted in position 4 and a dyeing set | L'OREAL (FR) | 1998-07-01 | — | — | EP | claimed |
| WO-2011073151-A2 | METHOD FOR THE TWO-STEP DYEING OF KERATIN FIBRES, BY APPLICATION OF A COMPOSITION COMPRISING A NAPHTALENE DERIVATIVE, THEN ALKALINE TREATMENT. | L'OREAL (FR) | 2011-06-23 | — | — | WO | disclosed |
| EP-1555993-B1 | PERMANENT COLORING OF HAIR USING AN OXIDATION HAIR DYE PRECURSOR AND A METAL CYANATE | UNILEVER PLC (GB) | 2010-03-24 | — | — | EP | disclosed |
| EP-1555993-A2 | PERMANENT COLORING OF HAIR USING AN OXIDATION HAIR DYE PRECURSOR AND A METAL CYANATE | UNILEVER PLC (GB) | 2005-07-27 | — | — | EP | disclosed |
| US-6821302-B2 | Oxidation color dye comprising a metal cyanate, free of ammonia, without the pungent odor of ammonia | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-11-23 | — | — | US | disclosed |
| US-6758866-B2 | AQUEOUS SOLUTION OF CHELATE COMPOUND, OXIDATION COLOR DYE AND COUPLER | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-07-06 | — | — | US | disclosed |
| WO-2004039341-A2 | PERMANENT COLORING OF HAIR USING AN OXIDATION HAIR DYE PRECURSOR AND A METAL CYANATE | UNILEVER PLC (GB) | 2004-05-13 | — | — | WO | disclosed |
| US-20040083557-A1 | Permanent coloring of hair using carbonate salts and bicarbonate salts and using percarbamic acid precursors | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-05-06 | — | — | US | disclosed |
| US-20040019980-A1 | One step hair coloring compositions using salts | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-02-05 | — | — | US | disclosed |
| US-20030135935-A1 | Enhanced color deposition for hair with sequestering agents | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-07-24 | — | — | US | disclosed |
| WO-2003053386-A1 | ENHANCED COLOUR DEPOSITION FOR HAIR WITH SEQUESTERING AGENTS | UNILEVER PLC (GB) | 2003-07-03 | — | — | WO | disclosed |
| EP-0850635-B1 | Process for oxydative dyeing of keratinic fibers in two steps with a manganese salt or a manganese complex and a 1-naphtol substituted in position 4 and a dyeing set | OREAL (FR) | 1999-07-14 | — | — | EP | disclosed |
| US-5873910-A | IN FIRST STAGE APPLYING TO KERATIN FIBER A FIRST SOLUTION CONTAINING IN A DYEING MEDIUM A MANGANESE SALT AND/OR COMPLEX, IN SECOND STAGE, APPLYING TO THE HAIR A SOLUTION WHICH CONTAINS 4-SUBSTITUED NAPHTHOL/1-/ AND AN OXIDIZER | L'OREAL (FR) | 1999-02-23 | — | — | US | disclosed |
| EP-0850635-A1 | Process for oxydative dyeing of keratinic fibers in two steps with a manganese salt or a manganese complex and a 1-naphtol substituted in position 4 and a dyeing set | L'OREAL (FR) | 1998-07-01 | — | — | EP | disclosed |