Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 4/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 13/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.38 |
| ▸ | TSHR | P16473 | 11/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 11/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20256613 | 0.93 | SCN1A (0.50) | SCN1ASCN5ASCN8ACYP1A2CYP3A4 | |
| SCHEMBL20256174 | 0.91 | CYP1A2 (0.37) | SCN1ASCN5ASCN8ACYP1A2CYP3A4 | |
| SCHEMBL20256159 | 0.89 | KMT2A (0.39) | SCN1ASCN5ASCN8ACYP1A2CYP3A4 | |
| SCHEMBL20256130 | 0.89 | CYP1A2 (0.37) | SCN1ASCN5ASCN8ACYP1A2CYP3A4 | |
| SCHEMBL20256499 | 0.89 | SCN1A (0.48) | SCN1ASCN5ASCN8ACYP1A2CYP3A4 | |
| SCHEMBL20256699 | 0.88 | KDM4E (0.38) | SCN1ASCN5ASCN8ACYP1A2CYP3A4 | |
| SCHEMBL20256424 | 0.88 | SCN1A (0.36) | SCN1ASCN5ASCN8ACYP1A2CYP3A4 | |
| SCHEMBL20256471 | 0.87 | ALDH1A1 (0.37) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL20256286 | 0.87 | MAPT (0.37) | SCN1ASCN5ASCN8ACYP1A2CYP3A4 | |
| SCHEMBL20256834 | 0.86 | CYP1A2 (0.37) | SCN1ASCN5ASCN8ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018106284-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2018-06-14 | — | — | WO | disclosed |