Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20256471 | 0.94 | ALDH1A1 (0.37) | MAPTLMNACLK4MEN1KMT2A | |
| SCHEMBL20256130 | 0.93 | CYP1A2 (0.37) | LMNACLK4MEN1KMT2ACYP1A2 | |
| SCHEMBL20256548 | 0.93 | MEN1 (0.34) | MAPTLMNACLK4MEN1KMT2A | |
| SCHEMBL20256212 | 0.92 | MITF (0.40) | MAPTLMNACLK4MEN1KMT2A | |
| SCHEMBL20256159 | 0.91 | KMT2A (0.39) | LMNACLK4MEN1KMT2ACYP1A2 | |
| SCHEMBL20256524 | 0.90 | KDM4E (0.36) | MAPTLMNACLK4MEN1KMT2A | |
| SCHEMBL20256424 | 0.90 | SCN1A (0.36) | MAPTLMNACLK4MEN1KMT2A | |
| SCHEMBL20256174 | 0.87 | CYP1A2 (0.37) | MAPTLMNACLK4MEN1KMT2A | |
| SCHEMBL20256699 | 0.87 | KDM4E (0.38) | MAPTLMNACLK4MEN1KMT2A | |
| SCHEMBL20256162 | 0.87 | SCN1A (0.41) | MAPTLMNACLK4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018106284-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2018-06-14 | — | — | WO | disclosed |