Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20256130 | 0.87 | CYP1A2 (0.37) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL19634123 | 0.82 | SCN8A (0.50) | TSHRALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL19633978 | 0.82 | MEN1 (0.38) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL19634063 | 0.82 | MEN1 (0.36) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL19634093 | 0.82 | MEN1 (0.36) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL20256717 | 0.80 | POLB (0.37) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL20256524 | 0.80 | KDM4E (0.36) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL20256471 | 0.80 | ALDH1A1 (0.37) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL20256286 | 0.80 | MAPT (0.37) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL20256536 | 0.80 | MEN1 (0.37) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018106284-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2018-06-14 | — | — | WO | disclosed |