Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 4/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20238210 | 0.83 | PDE2A (0.43) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| SCHEMBL14987514 | 0.83 | PDE2A (0.43) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| SCHEMBL18449424 | 0.83 | PDE2A (0.43) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| SCHEMBL248835 | 0.81 | DGAT1 (0.38) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| SCHEMBL29604357 | 0.81 | DGAT1 (0.38) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| Hydrochloric Acid SCHEMBL20238110 | 0.81 | PDE2A (0.42) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| SCHEMBL18449718 | 0.81 | DPP4 (0.37) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| Hydrochloric Acid SCHEMBL18449516 | 0.81 | PDE2A (0.42) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| SCHEMBL18449939 | 0.81 | DPP4 (0.37) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| SCHEMBL18488024 | 0.81 | DPP4 (0.37) | DPP4DGAT1KDM1AKDM1BAPLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018106284-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2018-06-14 | — | — | WO | disclosed |