Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18449718 | 1.00 | DPP4 (0.37) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| SCHEMBL18449939 | 1.00 | DPP4 (0.37) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| SCHEMBL20256754 | 0.81 | DPP4 (0.40) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| SCHEMBL248835 | 0.81 | DGAT1 (0.38) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| SCHEMBL29604357 | 0.81 | DGAT1 (0.38) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| SCHEMBL29668972 | 0.79 | CES2 (0.42) | DPP4KDM1AKDM1BIDO1 | |
| SCHEMBL20238308 | 0.79 | CES2 (0.42) | DPP4KDM1AKDM1BIDO1 | |
| SCHEMBL20238309 | 0.79 | CES2 (0.42) | DPP4KDM1AKDM1BIDO1 | |
| SCHEMBL14987514 | 0.78 | PDE2A (0.43) | DPP4DGAT1KDM1AKDM1BAPLNR | |
| SCHEMBL20238210 | 0.78 | PDE2A (0.43) | DPP4DGAT1KDM1AKDM1BAPLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137547-B | Heterocyclic compounds useful as TNF alpha modulators | 百时美施贵宝公司 | 2021-11-12 | — | — | CN | disclosed |
| WO-2017023905-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF TNF ALPHA | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-02-09 | — | — | WO | disclosed |