Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 5/20 | 0.40 |
| ▸ | FES | P07332 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20241410 | 0.92 | HDAC8 (0.41) | PTAFRFESRETMARK3TYK2 | |
| SCHEMBL21528433 | 0.92 | HDAC8 (0.41) | PTAFRFESRETMARK3TYK2 | |
| SCHEMBL20242089 | 0.92 | FAAH (0.41) | NAMPTFAAH | |
| SCHEMBL20241402 | 0.92 | FAAH (0.41) | NAMPTFAAH | |
| SCHEMBL20257431 | 0.92 | FAAH (0.38) | NAMPTFAAHASAH1 | |
| SCHEMBL20257511 | 0.88 | FAAH (0.40) | HDAC8KMT2ANAMPTFAAH | |
| SCHEMBL20257512 | 0.86 | EPHX1 (0.38) | PTAFRFESRETMARK3TYK2 | |
| SCHEMBL7562309 | 0.85 | OPRL1 (0.43) | FAAH | |
| SCHEMBL13054036 | 0.85 | OPRL1 (0.43) | FAAH | |
| SCHEMBL8203469 | 0.85 | OPRL1 (0.43) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018106519-A1 | HETEROCYCLIC COMPOUNDS AS HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2018-06-14 | — | — | WO | disclosed |