Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20261073 | 0.87 | MEN1 (0.47) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL22813895 | 0.84 | ZDHHC20 (0.49) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8115453 | 0.84 | MEN1 (0.49) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8101448 | 0.84 | MEN1 (0.49) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL26801512 | 0.84 | MEN1 (0.49) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8108773 | 0.84 | MEN1 (0.49) | MEN1KMT2ATHRBHTTMAPT | |
| Ethylene Glycol SCHEMBL7253062 | 0.84 | CA12 (0.47) | MEN1KMT2ATSHRZDHHC20CES2 | |
| SCHEMBL24288771 | 0.83 | MEN1 (0.47) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL20261072 | 0.82 | LMNA (0.48) | MEN1KMT2ATSHRZDHHC20CES2 | |
| SCHEMBL22986005 | 0.82 | CA12 (0.45) | MEN1KMT2ATHRBTSHRZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114937-A2 | FLUORINATED CATIONIC LIPIDS FOR USE IN LIPID NANOPARTICLES | Acuitas Therapeutics, Inc. (CA) | 2023-06-22 | — | — | WO | disclosed |
| WO-2021030701-A1 | IMPROVED LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS | Acuitas Therapeutics, Inc. (CA) | 2021-02-18 | — | — | WO | disclosed |
| WO-2018107026-A1 | DELIVERY OF TARGET SPECIFIC NUCLEASES | SANGAMO THERAPEUTICS, INC. (US) | 2018-06-14 | — | — | WO | disclosed |