SCHEMBL20262201

SCHEMBL20262201

C=C(CCOCC)C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.44
ALDH1A1 P00352 2/20 0.40
TSHR P16473 2/20 0.40
ALOX15 P16050 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20379561 0.96 THRB (0.46) THRBALDH1A1TSHRALOX15TDP1
SCHEMBL28833990 0.82 TSHR (0.43) THRBALDH1A1TSHR
SCHEMBL43126 0.80 THRB (0.45) THRBALDH1A1TSHRALOX15TDP1
SCHEMBL10935297 0.79 TDP1 (0.37) TDP1
SCHEMBL29490783 0.78 TSHR (0.43) THRBALDH1A1TSHR
SCHEMBL29223377 0.78 TSHR (0.38) TSHRTDP1
SCHEMBL1557468 0.77
SCHEMBL1011995 0.77
SCHEMBL289084 0.77 THRB (0.47) THRBALDH1A1TSHREPHX2
SCHEMBL3459308 0.77 THRB (0.52) THRBALDH1A1TSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4241797-A2 (METH)ACRYLAMIDE POLYMERS FOR CONTACT LENS AND INTRAOCULAR LENS Benz Research And Development Corporation (US) 2023-09-13 EP disclosed
CN-110462448-B Hydrophilic material with high refractive index 宾视研发公司 2023-08-01 CN disclosed
US-10894111-B2 High refractive index hydrophilic materials BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2021-01-19 US disclosed
US-20180169296-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-06-21 US disclosed