Diphenamide

Diphenamide

SCHEMBL2026352

C1CCCCC1.CN(C)C(=O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.53
OPRL1 P41146 1/20 0.53
KDM4E B2RXH2 1/20 0.50
ATM Q13315 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TDP1 Q9NUW8 2/20 0.49
TACR1 P25103 3/20 0.47
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenamide SCHEMBL39339 0.94 ALDH1A1 (0.55) OPRM1OPRL1KDM4EATMALDH1A1
Diphenamide SCHEMBL6910614 0.94 ALDH1A1 (0.55) OPRM1OPRL1KDM4EATMALDH1A1
Diphenamide SCHEMBL9202269 0.94 ALDH1A1 (0.55) OPRM1OPRL1KDM4EATMALDH1A1
Diphenamide SCHEMBL11211674 0.92 ALDH1A1 (0.53) OPRM1OPRL1KDM4EATMALDH1A1
Diphenamide SCHEMBL2051916 0.92 ALDH1A1 (0.53) OPRM1OPRL1KDM4EATMALDH1A1
Diphenamide SCHEMBL23924070 0.92 ALDH1A1 (0.53) OPRM1OPRL1KDM4EATMALDH1A1
Diphenamide SCHEMBL10338756 0.92 ALDH1A1 (0.53) OPRM1OPRL1KDM4EATMALDH1A1
Diphenamide SCHEMBL3951388 0.92 ALDH1A1 (0.53) OPRM1OPRL1KDM4EATMALDH1A1
Diphenamide SCHEMBL22345014 0.92 ALDH1A1 (0.53) OPRM1OPRL1KDM4EATMALDH1A1
Diphenamide SCHEMBL23534079 0.92 ALDH1A1 (0.53) OPRM1OPRL1KDM4EATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110178218-A1 IONIC ORGANIC COMPOUND, PRODUCTION METHOD THEREOF, HYDROGELLING AGENT COMPOSED OF THE IONIC ORGANIC COMPOUND, HYDROGEL CONTAINING SAME, METHANOL GELLING AGENT, METHANOL GEL CONTAINING SAME, AND CARBON NANOTUBE DISPERSANT National Institute of Avanced Industrial Science and Technology (JP) 2011-07-21 US claimed
EP-2330143-A1 IONIC ORGANIC COMPOUND, PRODUCTION METHOD THEREOF, HYDROGELLING AGENT COMPOSED OF THE IONIC ORGANIC COMPOUND, HYDROGEL CONTAINING SAME, METHANOL GELLING AGENT, METHANOL GEL CONTAINING SAME, AND CARBON NANOTUBE DISPERSANT National Institute of Advanced Industrial Science And Technology (JP) 2011-06-08 EP claimed
CN-100528951-C Method of making and using a superabsorbent polymer product including a bioactive, growth-promoting additive ABSORBENT TECHNOLOGIES INC (US) 2009-08-19 CN claimed
US-7494697-B2 Substrate of artificial leather including ultrafine fibers and methods for making the same SAN FANG CHEMICAL INDUSTRY CO., LTD. (TW) 2009-02-24 US claimed
CN-1906243-A Method of making and using a superabsorbent polymer product including a bioactive, growth-promoting additive ABSORBENT TECHNOLOGIES INC (US) 2007-01-31 CN claimed
US-20060263601-A1 Substrate of artificial leather including ultrafine fibers and methods for making the same SAN FANG CHEMICAL INDUSTRY CO., LTD. (TW) 2006-11-23 US claimed
CN-118759815-A Printing apparatus, sealing member and molding method thereof 苏州市创怡盛实业有限公司 2024-10-11 CN disclosed
CN-116987277-A Chiral cadmium complex of alanine derivative, preparation method and application thereof 河北师范大学 2023-11-03 CN disclosed
CN-111479802-B Process for producing dicyanocyclohexane and bis (aminomethyl) cyclohexane 三菱瓦斯化学株式会社 2023-07-28 CN disclosed
CN-111479802-A Process for producing dicyanocyclohexane and bis (aminomethyl) cyclohexane 三菱瓦斯化学株式会社 2020-07-31 CN disclosed
EP-2185358-B1 MULTILAYER FILM HAVING AN ACTIVE OXYGEN BARRIER LAYER WITH RADIATION ENHANCED ACTIVE BARRIER PROPERTIES CRYOVAC INC (US) 2020-06-17 EP disclosed
US-20200180281-A1 VACUUM SKIN PACKAGES FOR SOFT PRODUCTS AND VACUUM SKIN METHOD OF PACKAGING CRYOVAC LLC (US) 2020-06-11 US disclosed
EP-3645283-A1 VACUUM SKIN PACKAGES FOR SOFT PRODUCTS AND VACUUM SKIN METHOD OF PACKAGING Cryovac, LLC (US) 2020-05-06 EP disclosed
EP-1070748-A1 Powder coating compositions, their preparation and use E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-01-24 EP disclosed
EP-1051264-A1 METHOD AND COMPOSITIONS FOR PROTECTING CIVIL INFRASTRUCTURE NORTH CAROLINA STATE UNIVERSITY (US) 2000-11-15 EP disclosed
US-6127000-A PROVIDING MIXTURE CONSISTING OF CARBON DIOXIDE AND FLUOROPOLYETHER, WHEREIN FLUOROPOLYETHER HAS ANCHORING GROUP; SPRAYIN MIXTURE ON POROUS CIVIL INFRASTRUCTURE SUBSTRATE TO PENETRATE PORES OF SUBSTRATE AND BECOME INCORPORATED NORTH CAROLINA STATE UNIVERSITY (US) 2000-10-03 US disclosed
US-6114489-A POWDER COATING COMPOSITIONS CONTAINING NOVEL ALIPHATIC HYPERBRANCHED POLYESTER POLYMERS, WHICH FUNCTION EITHER AS POLYMERIC CROSSLINKERS OR AS FLOW AND LEVELING AGENTS HERBERTS GMBH (DE) 2000-09-05 US disclosed
WO-1999019080-A1 METHOD AND COMPOSITIONS FOR PROTECTING CIVIL INFRASTRUCTURE NORTH CAROLINA STATE UNIVERSITY (US) 1999-04-22 WO disclosed
WO-1996033699-A1 DIAMIDE-DICARBOXYLIC ACID MICROSPHERES EMISPHERE TECHNOLOGIES, INC. (US) 1996-10-31 WO disclosed
US-5491009-A OXYGEN BARRIER IMPLOSION RESISTANT FILM FOR FOOD PACCKAGES W. R. GRACE & CO.-CONN. (US) 1996-02-13 US disclosed