Diphenamide

Diphenamide

SCHEMBL22345014

CN(C)C(=O)C(c1ccccc1)c1ccccc1.[Ni]

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
KDM4E B2RXH2 1/20 0.53
ATM Q13315 1/20 0.53
TDP1 Q9NUW8 2/20 0.51
OPRM1 P35372 1/20 0.51
OPRL1 P41146 1/20 0.51
TACR1 P25103 3/20 0.50
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
CRHBP P24387 1/20 0.49
CRHR2 Q13324 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenamide SCHEMBL6910614 0.98 ALDH1A1 (0.55) ALDH1A1KDM4EATMTDP1OPRM1
Diphenamide SCHEMBL39339 0.98 ALDH1A1 (0.55) ALDH1A1KDM4EATMTDP1OPRM1
Diphenamide SCHEMBL9202269 0.98 ALDH1A1 (0.55) ALDH1A1KDM4EATMTDP1OPRM1
Diphenamide SCHEMBL2051916 0.96 ALDH1A1 (0.53) ALDH1A1KDM4EATMTDP1OPRM1
Diphenamide SCHEMBL11211674 0.96 ALDH1A1 (0.53) ALDH1A1KDM4EATMTDP1OPRM1
Diphenamide SCHEMBL23534079 0.96 ALDH1A1 (0.53) ALDH1A1KDM4EATMTDP1OPRM1
Diphenamide SCHEMBL2516775 0.96 ALDH1A1 (0.53) ALDH1A1KDM4EATMTDP1OPRM1
Diphenamide SCHEMBL12477138 0.96 ALDH1A1 (0.53) ALDH1A1KDM4EATMTDP1OPRM1
Diphenamide SCHEMBL23924070 0.96 ALDH1A1 (0.53) ALDH1A1KDM4EATMTDP1OPRM1
Diphenamide SCHEMBL10338756 0.96 ALDH1A1 (0.53) ALDH1A1KDM4EATMTDP1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111132987-B Vapor deposition precursor having excellent thermal stability and reactivity and method for preparing the same 韩松化学株式会社 2023-02-24 CN disclosed
US-20200266056-A1 VAPOR DEPOSITION PRECURSOR HAVING EXCELLENT THERMAL STABILITY AND REACTIVITY AND PREPARING METHOD THEREFOR HANSOL CHEMICAL CO., LTD. (KR) 2020-08-20 US disclosed
CN-111132987-A Vapor deposition precursor having excellent thermal stability and reactivity and method for preparing the same 韩松化学株式会社 2020-05-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200266056-A1 VAPOR DEPOSITION PRECURSOR HAVING EXCELLENT THERMAL STABILITY AND REACTIVITY AND PREPARING METHOD THEREFOR SLC39A11, CAD, ADH1A ALDH1A1 129/4885KDM4E 1390/4885ATM 2816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.