Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 12/20 | 0.58 |
| ▸ | HSD17B1 | P14061 | 11/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20264682 | 1.00 | HSD17B2 (0.58) | HSD17B2HSD17B1MTNR1AMTNR1B | |
| SCHEMBL29940760 | 1.00 | HSD17B2 (0.58) | HSD17B2HSD17B1MTNR1AMTNR1B | |
| SCHEMBL28148839 | 0.83 | HSD17B2 (0.56) | HSD17B2HSD17B1MTNR1AMTNR1B | |
| SCHEMBL11027897 | 0.82 | HSD17B2 (0.61) | HSD17B2HSD17B1MTNR1AMTNR1B | |
| SCHEMBL10940468 | 0.81 | HSD17B2 (0.60) | HSD17B2HSD17B1MTNR1AMTNR1B | |
| SCHEMBL20264517 | 0.79 | HSD17B2 (0.61) | HSD17B2HSD17B1MTNR1AMTNR1B | |
| SCHEMBL20264598 | 0.79 | HSD17B2 (0.55) | HSD17B2HSD17B1MTNR1AMTNR1B | |
| SCHEMBL20264666 | 0.79 | HSD17B2 (0.55) | HSD17B2HSD17B1MTNR1AMTNR1B | |
| SCHEMBL20264661 | 0.79 | HSD17B2 (0.55) | HSD17B2HSD17B1MTNR1AMTNR1B | |
| SCHEMBL29940504 | 0.79 | HSD17B2 (0.55) | HSD17B2HSD17B1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3339279-B1 | NOVEL ORGANOLEPTIC COMPOUNDS | INT FLAVORS & FRAGRANCES INC (US) | 2019-09-11 | — | — | EP | disclosed |
| EP-3339279-B1 | NOVEL ORGANOLEPTIC COMPOUNDS | INT FLAVORS & FRAGRANCES INC (US) | 2019-09-11 | — | — | EP | disclosed |
| US-10329516-B2 | Organoleptic compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2019-06-25 | — | — | US | disclosed |
| US-10329516-B2 | Organoleptic compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2019-06-25 | — | — | US | disclosed |
| EP-3339279-A1 | NOVEL ORGANOLEPTIC COMPOUNDS | International Flavors & Fragrances Inc. (US) | 2018-06-27 | — | — | EP | disclosed |
| EP-3339279-A1 | NOVEL ORGANOLEPTIC COMPOUNDS | International Flavors & Fragrances Inc. (US) | 2018-06-27 | — | — | EP | disclosed |
| US-20180171265-A1 | NOVEL ORGANOLEPTIC COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2018-06-21 | — | — | US | disclosed |
| US-20180171265-A1 | NOVEL ORGANOLEPTIC COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2018-06-21 | — | — | US | disclosed |
| US-20180171265-A1 | NOVEL ORGANOLEPTIC COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2018-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329516-B2 | Organoleptic compounds | TRPA1, TRPV1, TRPV5 | HSD17B2 1957/4885HSD17B1 2255/4885MTNR1A 1788/4885 |
| US-20180171265-A1 | NOVEL ORGANOLEPTIC COMPOUNDS | TRPA1, TRPV1, TRPV5 | HSD17B2 2203/4885HSD17B1 2424/4885MTNR1A 2017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.