SCHEMBL20268268

SCHEMBL20268268

OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)N[C@H]1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 4/20 0.46
▸ ADORA2A P29274 4/20 0.46
▸ SMN1; SMN2 Q16637 3/20 0.46
▸ SLC29A1 Q99808 3/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ ADORA2B P29275 2/20 0.46
▸ ADORA1 P30542 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ DPP4 P27487 1/20 0.46
▸ SLC28A1 O00337 1/20 0.46
▸ MAP3K7 O43318 1/20 0.46
▸ SLC28A2 O43868 1/20 0.46
▸ GAPDH P04406 1/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ STAT6 P42226 1/20 0.46
▸ PI4KA P42356 1/20 0.46
▸ PI4K2B Q8TCG2 1/20 0.46
▸ DOT1L Q8TEK3 1/20 0.46
▸ PI4K2A Q9BTU6 1/20 0.46
▸ SLC28A3 Q9HAS3 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL343881 1.00 ADORA3 (0.46) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
SCHEMBL343882 1.00 ADORA3 (0.46) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL298755 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL15804 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL4110068 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL6748954 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL12763613 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL20138477 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL2229394 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1
Inosine SCHEMBL330178 0.77 SLC29A1 (0.75) ADORA3ADORA2ASMN1; SMN2SLC29A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018251-B2 Method for synthesis of polynucleotides using a diverse library of oligonucleotides RIBBON BIOLABS GMBH (AT) 2024-06-25 — — US disclosed
EP-3694994-B1 A NOVEL METHOD FOR SYNTHESIS OF POLYNUCLEOTIDES USING A DIVERSE LIBRARY OF OLIGONUCLEOTIDES RIBBON BIOLABS GMBH (AT) 2024-06-12 — — EP disclosed
US-20230317208-A1 BIOPOLYMER SYNTHESIS RIBBON BIOLABS GMBH (AT) 2023-10-05 — — US disclosed
WO-2023187175-A1 ASYMMETRIC ASSEMBLY OF POLYNUCLEOTIDES RIBBON BIOLABS GMBH (AT) 2023-10-05 — — WO disclosed
WO-2023187214-A1 BIOPOLYMER SYNTHESIS RIBBON BIOLABS GMBH (AT) 2023-10-05 — — WO disclosed
US-20220348902-A1 METHOD FOR SYNTHESIS OF POLYNUCLEOTIDES USING A DIVERSE LIBRARY OF OLIGONUCLEOTIDES RIBBON BIOLABS GMBH (AT) 2022-11-03 — — US disclosed
US-11352619-B2 Method for synthesis of polynucleotides using a diverse library of oligonucleotides RIBBON BIOLABS GMBH (AT) 2022-06-07 — — US disclosed
US-20220162596-A1 A LIBRARY OF POLYNUCLEOTIDES RIBBON BIOLABS GMBH (AT) 2022-05-26 — — US disclosed
EP-3953466-A1 A LIBRARY OF POLYNUCLEOTIDES Ribbon Biolabs GmbH (AT) 2022-02-16 — — EP disclosed
WO-2020208234-A1 A LIBRARY OF POLYNUCLEOTIDES RIBBON BIOLABS GMBH (AT) 2020-10-15 — — WO disclosed
US-20200283756-A1 A NOVEL METHOD FOR SYNTHESIS OF POLYNUCLEOTIDES USING A DIVERSE LIBRARY OF OLIGONUCLEOTIDES VLADAR, Harold Paul (AT) 2020-09-10 — — US disclosed
EP-3694994-A1 A NOVEL METHOD FOR SYNTHESIS OF POLYNUCLEOTIDES USING A DIVERSE LIBRARY OF OLIGONUCLEOTIDES Ribbon Biolabs GmbH (AT) 2020-08-19 — — EP disclosed
US-10669537-B2 Mutagenizing intracellular nucleic acids BIOLOGICAL RESEARCH CENTRE (HU) 2020-06-02 — — US disclosed
EP-3526327-B1 MUTAGENIZING INTRACELLULAR NUCLEIC ACIDS BIOLOGICAL RES CENTRE (HU) 2020-02-19 — — EP disclosed
EP-3526327-A1 MUTAGENIZING INTRACELLULAR NUCLEIC ACIDS Biological Research Centre, Hungarian Academy of Sciences (HU) 2019-08-21 — — EP disclosed
WO-2019073072-A1 A NOVEL METHOD FOR SYNTHESIS OF POLYNUCLEOTIDES USING A DIVERSE LIBRARY OF OLIGONUCLEOTIDES RIBBON BIOLABS GMBH (AT) 2019-04-18 — — WO disclosed
WO-2018108987-A1 MUTAGENIZING INTRACELLULAR NUCLEIC ACIDS BIOLOGICAL RESEARCH CENTRE, HUNGARIAN ACADEMY OF SCIENCES (HU) 2018-06-21 — — WO disclosed
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