Inosine

Inosine

SCHEMBL298755

OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)C(O)C1O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 4/20 0.75
ADORA3 P0DMS8 2/20 0.75
MAPK1 P28482 2/20 0.75
ADORA1 P30542 2/20 0.75
SMN1; SMN2 Q16637 2/20 0.75
DPP4 P27487 1/20 0.75
MEN1 O00255 1/20 0.75
SLC28A1 O00337 1/20 0.75
MAP3K7 O43318 1/20 0.75
SLC28A2 O43868 1/20 0.75
GAPDH P04406 1/20 0.75
ADORA2A P29274 1/20 0.75
ADORA2B P29275 1/20 0.75
STAT6 P42226 1/20 0.75
PI4KA P42356 1/20 0.75
KMT2A Q03164 1/20 0.75
PI4K2B Q8TCG2 1/20 0.75
DOT1L Q8TEK3 1/20 0.75
PI4K2A Q9BTU6 1/20 0.75
SLC28A3 Q9HAS3 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Inosine SCHEMBL12763613 1.00 SLC29A1 (0.75) SLC29A1ADORA3MAPK1ADORA1SMN1; SMN2
Inosine SCHEMBL2229394 1.00 SLC29A1 (0.75) SLC29A1ADORA3MAPK1ADORA1SMN1; SMN2
Inosine SCHEMBL18653532 1.00 SLC29A1 (0.75) SLC29A1ADORA3MAPK1ADORA1SMN1; SMN2
Inosine SCHEMBL2046912 1.00 SLC29A1 (0.75) SLC29A1ADORA3MAPK1ADORA1SMN1; SMN2
Inosine SCHEMBL20138477 1.00 SLC29A1 (0.75) SLC29A1ADORA3MAPK1ADORA1SMN1; SMN2
Inosine SCHEMBL15804 1.00 SLC29A1 (0.75) SLC29A1ADORA3MAPK1ADORA1SMN1; SMN2
Inosine SCHEMBL4110068 1.00 SLC29A1 (0.75) SLC29A1ADORA3MAPK1ADORA1SMN1; SMN2
Inosine SCHEMBL6748954 1.00 SLC29A1 (0.75) SLC29A1ADORA3MAPK1ADORA1SMN1; SMN2
Inosine SCHEMBL330178 1.00 SLC29A1 (0.75) SLC29A1ADORA3MAPK1ADORA1SMN1; SMN2
Inosine SCHEMBL29436140 1.00 SLC29A1 (0.75) SLC29A1ADORA3MAPK1ADORA1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630851-B2 Polynucleotide modification methods OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-19 US claimed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US claimed
US-20230250474-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-08-10 US claimed
US-11542551-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-01-03 US claimed
US-20220186274-A1 POLYNUCLEOTIDE MODIFICATION METHODS OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2022-06-16 US claimed
US-20200318179-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2020-10-08 US claimed
CN-106232834-B Sample preparation method 牛津纳米孔技术公司 2020-09-22 CN claimed
US-10669578-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES LTD. (GB) 2020-06-02 US claimed
CN-105705656-B Method of producing a composite material 牛津纳米孔技术公司 2020-02-21 CN claimed
EP-3033435-B1 METHOD FOR FRAGMENTING NUCLEIC ACID BY MEANS OF TRANSPOSASE OXFORD NANOPORE TECH LTD (GB) 2019-07-24 EP claimed
WO-2015124935-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-08-27 WO claimed
EP-2895618-A1 SAMPLE PREPARATION METHOD Oxford Nanopore Technologies Limited (GB) 2015-07-22 EP claimed
WO-2015022544-A1 METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-02-19 WO claimed
WO-2014108529-A1 INHIBITORY OLIGONUCLEOTIDES AND THEIR USE IN THERAPY SAREPTA THERAPEUTICS, INC. (US) 2014-07-17 WO claimed
WO-2014041337-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2014-03-20 WO claimed
WO-2010056795-A1 NOVEL SYNTHETIC DINUCLEOSIDE POLYPHOSPHATE ANALOGS AND THEIR USE AS NEW THERAPEUTIC AND/OR DIAGNOSTIC MODALITIES ZATA PHARMACEUTICALS, INC. (US) 2010-05-20 WO claimed
EP-1262564-A2 Dna sequencing by mass spectrometry SEQUENOM, INC. (US) 2002-12-04 EP claimed
US-6200747-B1 AMPLIFYING NUCLEIC ACIDS BY POLYMERASE CHAIN REACTION; CALIBRATION NORTH SHORE UNIVERSITY HOSPITAL RESEARCH CORP. 2001-03-13 US claimed
US-5691141-A SOLID PHASE SYNTHESIS, LINKING LARGE MOLECULES TO NUCLEOTIDES TO DIFFERENTIATE SEQUENOM, INC. (US) 1997-11-25 US claimed
US-5658764-A METHOD FOR DETERMINING WHETHER AN INDIVIDUAL IS A CARRIER FOR OR AFFLICTED WITH A FRAGILE X MUTATION NORTH SHORE UNIVERSITY HOSPITAL RESEARCH CORP. (US) 1997-08-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM SLC29A1 90/4885ADORA3 1197/4885MAPK1 3352/4885
US-12630851-B2 Polynucleotide modification methods PNP, NT5C3B, UNG SLC29A1 53/4885ADORA3 201/4885MAPK1 3096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.