⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13244968 | 1.00 | — | — | |
| SCHEMBL166753 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL19837180 | 0.97 | PTGS1 (0.46) | — | |
| SCHEMBL18774920 | 0.78 | ALDH1A1 (0.41) | — | |
| SCHEMBL24489346 | 0.77 | PTGS1 (0.44) | — | |
| SCHEMBL5288286 | 0.77 | ALDH1A1 (0.44) | — | |
| SCHEMBL296273 | 0.77 | — | — | |
| SCHEMBL11685771 | 0.77 | — | — | |
| SCHEMBL5299472 | 0.77 | — | — | |
| SCHEMBL17414698 | 0.77 | PTGS1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 452 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067394-A1 | HALOGEN-SUBSTITUTED EXATECAN AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 杭州爱科瑞思生物医药有限公司 | 2025-04-03 | — | — | WO | claimed |
| US-20210115087-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIV ROCHESTER (US) | 2021-04-22 | — | — | US | claimed |
| US-20190241615-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIVERSITY OF ROCHESTER | 2019-08-08 | — | — | US | claimed |
| EP-3475294-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | The University of Rochester (US) | 2019-05-01 | — | — | EP | claimed |
| WO-2017223207-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIVERSITY OF ROCHESTER (US) | 2017-12-28 | — | — | WO | claimed |
| EP-0914333-B1 | PEPTIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2004-11-24 | — | — | EP | claimed |
| EP-0932618-B1 | PEPTIDE ANALOGUES CONTAINING A 7-MEMBERED LACTAM RING | ASTRAZENECA AB (SE) | 2003-12-10 | — | — | EP | claimed |
| US-20030195158-A1 | Peptide derivatives | SYNGENTA LIMITED (GB) | 2003-10-16 | — | — | US | claimed |
| EP-0946589-B1 | INHIBITORS OF PEPTIDE BINDING TO MHC CLASS II PROTEINS | ASTRAZENECA AB (SE) | 2003-10-01 | — | — | EP | claimed |
| US-6541453-B2 | Amino acid sequences for use in the treatment of autoimmune or inflammatory diseases | SYNGENTA LIMITED (GB) | 2003-04-01 | — | — | US | claimed |
| EP-0914333-A1 | PEPTIDE DERIVATIVES | ZENECA LIMITED (GB) | 1999-05-12 | — | — | EP | claimed |
| EP-0882066-A1 | PEPTIDE DERIVATIVES | ZENECA LIMITED (GB) | 1998-12-09 | — | — | EP | claimed |
| EP-0750489-B1 | INHIBITION OF HAIR GROWTH | HANDELMAN JOSEPH H (US) | 1998-11-18 | — | — | EP | claimed |
| WO-1998025951-A1 | INHIBITORS OF PEPTIDE BINDING TO MHC CLASS II PROTEINS | ZENECA LIMITED (GB) | 1998-06-18 | — | — | WO | claimed |
| WO-1998023644-A1 | PEPTIDE DERIVATIVES | ZENECA LIMITED (GB) | 1998-06-04 | — | — | WO | claimed |
| WO-1998017680-A1 | PEPTIDE ANALOGUES CONTAINING A 7-MEMBERED LACTAM RING | ZENECA LIMITED (GB) | 1998-04-30 | — | — | WO | claimed |
| WO-1997046578-A1 | PEPTIDE DERIVATIVES | ZENECA LIMITED (GB) | 1997-12-11 | — | — | WO | claimed |
| WO-1997031023-A1 | PEPTIDE DERIVATIVES | ZENECA LIMITED (GB) | 1997-08-28 | — | — | WO | claimed |
| US-5658885-A | OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| US-5455234-A | Applying inhibitor of cysteine pathway enzyme topically to skin; cosmetic for face, arms, legs | AHLUWALIA GURPREET S (US) | 1995-10-03 | — | — | US | claimed |