Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24489346 | 0.78 | PTGS1 (0.44) | PTGS1ALDH1A1MAPTSLC7A5SLC7A11 | |
| SCHEMBL7272092 | 0.78 | ALDH1A1 (0.44) | PTGS1ALDH1A1MAPTSLC7A5SLC7A11 | |
| SCHEMBL166753 | 0.77 | — | — | |
| SCHEMBL13244968 | 0.77 | — | — | |
| SCHEMBL202704 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL19837180 | 0.74 | PTGS1 (0.46) | PTGS1ALDH1A1MAPTGRB2SLC7A5 | |
| SCHEMBL17414168 | 0.74 | ALDH1A1 (0.52) | PTGS1ALDH1A1MAPTSLC7A5 | |
| SCHEMBL21688194 | 0.74 | ALDH1A1 (0.52) | PTGS1ALDH1A1MAPTSLC7A5 | |
| SCHEMBL18774919 | 0.74 | ALDH1A1 (0.41) | PTGS1ALDH1A1MAPT | |
| SCHEMBL23093886 | 0.74 | ALDH1A1 (0.52) | PTGS1ALDH1A1MAPTSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160002159-A1 | PERFLUORO-TERT-BUTYL HYDROXYPROLINE | ZONDLO NEAL (US) | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002159-A1 | PERFLUORO-TERT-BUTYL HYDROXYPROLINE | FIBP, HDGF, PLOD3 | PTGS1 1512/4885ALDH1A1 1073/4885MAPT 2089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.