Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20258199 | 0.87 | KCNJ1 (0.58) | MAPTKCNJ1TACR1KDM4EALDH1A1 | |
| SCHEMBL15347339 | 0.85 | ALDH1A1 (0.59) | MAPTACHEKDM4EALDH1A1LMNA | |
| SCHEMBL7563807 | 0.83 | ALDH1A1 (0.61) | KCNJ1TACR1KDM4EALDH1A1LMNA | |
| SCHEMBL922716 | 0.82 | KCNJ1 (0.74) | MAPTKCNJ1TACR1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7564284 | 0.82 | KCNJ1 (0.58) | KCNJ1TACR1KDM4EALDH1A1LMNA | |
| SCHEMBL7422612 | 0.80 | TACR1 (0.58) | KCNJ1TACR1KDM4EALDH1A1LMNA | |
| SCHEMBL20272181 | 0.80 | KDM4E (0.56) | MAPTTACR1KDM4EALDH1A1LMNA | |
| SCHEMBL15359665 | 0.80 | KDM4E (0.65) | MAPTKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL8718280 | 0.79 | KCNJ1 (0.61) | MAPTKCNJ1TACR1KDM4EALDH1A1 | |
| SCHEMBL8715361 | 0.79 | KCNJ1 (0.55) | KCNJ1TACR1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000452-B1 | Quinolone-based compounds, formulations, and uses thereof | UNIVERSITY OF SOUTH FLORIDA (US) | 2018-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000452-B1 | Quinolone-based compounds, formulations, and uses thereof | RECQL, NQO1, NQO2 | MAPT 1177/4885KCNJ1 3724/4885TACR1 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.