Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BCAT1 | P54687 | 6/20 | 0.38 |
| ▸ | IDO1 | P14902 | 5/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24496648 | 0.87 | PLA2G2A (0.35) | NPC1RAB9ATTRALDH1A1MAPT | |
| SCHEMBL25950252 | 0.80 | CHEK2 (0.35) | TTRHTR2B | |
| SCHEMBL25964611 | 0.78 | PTGER4 (0.34) | — | |
| SCHEMBL21599635 | 0.77 | PTGER4 (0.31) | — | |
| SCHEMBL26052202 | 0.76 | KDM4E (0.45) | RAB9AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL25546737 | 0.76 | NPC1 (0.42) | NPC1RAB9ATTRKDM4EMEN1 | |
| SCHEMBL20935810 | 0.76 | ALOX5 (0.36) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL26005669 | 0.75 | PTGER4 (0.35) | TTRHTR2B | |
| SCHEMBL19109779 | 0.74 | NPC1 (0.33) | NPC1RAB9AIDO1 | |
| SCHEMBL3557297 | 0.74 | TTR (0.53) | NPC1RAB9ATTRKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000694-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000694-B2 | Materials for organic electroluminescent devices | OR10J3, EPCAM, L1CAM | NPC1 3332/4885RAB9A 2692/4885TTR 1157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.