Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.57 |
| ▸ | AKT1 | P31749 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | NCF1 | P14598 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14515648 | 0.83 | CLK1 (0.68) | CCR5AKT1ADRB2NCF1PDGFRB | |
| SCHEMBL900183 | 0.81 | IDE (0.71) | AKT1ADRB2NCF1PDGFRBDRD2 | |
| SCHEMBL23362095 | 0.80 | KCNH2 (0.64) | AKT1ADRB2NCF1PDGFRBDRD2 | |
| SCHEMBL30060970 | 0.80 | PDGFRB (0.57) | CCR5AKT1ADRB2NCF1PDGFRB | |
| SCHEMBL899673 | 0.79 | IDE (0.49) | CCR5AKT1ADRB2NCF1PDGFRB | |
| SCHEMBL2422976 | 0.78 | PDGFRB (0.55) | AKT1ADRB2NCF1PDGFRBDRD2 | |
| SCHEMBL900431 | 0.78 | AKT1 (0.53) | CCR5AKT1ADRB2NCF1PDGFRB | |
| SCHEMBL900432 | 0.78 | AKT1 (0.53) | CCR5AKT1ADRB2NCF1PDGFRB | |
| SCHEMBL903257 | 0.78 | AKT1 (0.53) | CCR5AKT1ADRB2NCF1PDGFRB | |
| SCHEMBL20274115 | 0.77 | HTR1A (0.60) | NCF1DRD2DRD3SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |