Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MDH1 | P40925 | 1/20 | 0.39 |
| ▸ | MDH2 | P40926 | 1/20 | 0.39 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274192 | 0.91 | HRH3 (0.45) | MAOAPOLBNPSR1L3MBTL1HRH3 | |
| SCHEMBL20274213 | 0.91 | MAOA (0.47) | MAOAPIM1PIM2L3MBTL1HRH3 | |
| SCHEMBL15708019 | 0.90 | MAOA (0.50) | MAOAPOLBNPSR1PIM1PIM2 | |
| SCHEMBL20274152 | 0.85 | HTR2B (0.43) | HRH3HTR2BHTR1ACA2CA9 | |
| SCHEMBL20274139 | 0.82 | HRH4 (0.47) | POLBHRH3HTR2BHTR1ACA2 | |
| SCHEMBL20651225 | 0.82 | HTR2B (0.43) | HRH3HTR2BHTR1AOXTRCA2 | |
| SCHEMBL15750158 | 0.82 | PIM1 (0.41) | MAOAPOLBPIM1PIM2L3MBTL1 | |
| SCHEMBL23335840 | 0.81 | PIM1 (0.56) | PIM1PIM2HRH3 | |
| SCHEMBL20274177 | 0.80 | AKR1B1 (0.48) | MAOAL3MBTL1SIGMAR1MDH1MDH2 | |
| SCHEMBL20274217 | 0.80 | HTR2B (0.39) | HTR2BHTR1ACA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |