Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MDH1 | P40925 | 1/20 | 0.39 |
| ▸ | MDH2 | P40926 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274133 | 0.91 | MAOA (0.51) | HRH3L3MBTL1MAOAPOLBNPSR1 | |
| SCHEMBL20274213 | 0.83 | MAOA (0.47) | HRH3L3MBTL1MAOA | |
| SCHEMBL15708019 | 0.82 | MAOA (0.50) | HRH3L3MBTL1MAOAPOLBNPSR1 | |
| SCHEMBL20274152 | 0.81 | HTR2B (0.43) | HRH3 | |
| SCHEMBL20274139 | 0.79 | HRH4 (0.47) | HRH3POLB | |
| SCHEMBL20651225 | 0.79 | HTR2B (0.43) | HRH3OXTR | |
| SCHEMBL20274217 | 0.76 | HTR2B (0.39) | — | |
| SCHEMBL20274183 | 0.76 | HTR2B (0.54) | MAOA | |
| SCHEMBL15727609 | 0.74 | ENPP2 (0.36) | HRH3NPSR1 | |
| SCHEMBL20274177 | 0.74 | AKR1B1 (0.48) | L3MBTL1MAOASIGMAR1MDH1MDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |