Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.53 |
| ▸ | CNR2 | P34972 | 6/20 | 0.53 |
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13158252 | 0.85 | MAPK1 (0.45) | ARCNR2CNR1FFAR4FFAR1 | |
| SCHEMBL15686371 | 0.85 | CNR2 (0.55) | ARCNR2CNR1FFAR4FFAR1 | |
| SCHEMBL2630679 | 0.85 | CNR2 (0.45) | ARCNR2CNR1FFAR4FFAR1 | |
| SCHEMBL20651127 | 0.81 | CNR2 (0.56) | ARCNR2CNR1KDM4EMAPT | |
| SCHEMBL20651135 | 0.79 | CNR2 (0.54) | ARCNR2CNR1KDM4EMAPT | |
| SCHEMBL20274107 | 0.78 | TRPA1 (0.61) | ARCNR2CNR1 | |
| SCHEMBL20651344 | 0.78 | AR (0.53) | ARCNR2CNR1KDM4EMAPT | |
| SCHEMBL13456269 | 0.78 | AR (0.53) | ARCNR2CNR1KDM4EMAPT | |
| SCHEMBL15727592 | 0.76 | LMNA (0.52) | ARCNR2CNR1MAPTGAA | |
| SCHEMBL3792014 | 0.76 | MAPT (0.46) | KDM4EMAPTGAAMEN1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-A1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial Inc. (US) | 2019-01-16 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |