SCHEMBL20274175

SCHEMBL20274175

CN(c1ccc(C#N)c(C(F)(F)F)c1)C1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 20/20 0.52
PGR P06401 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4899422 0.99 AR (0.53) ARPGR
SCHEMBL28222088 0.86 AR (0.47) ARPGR
SCHEMBL16321814 0.84 AR (0.47) ARPGR
Hydrochloric Acid SCHEMBL17728456 0.84 NOS1 (0.49) ARPGR
Hydrochloric Acid SCHEMBL17728458 0.84 NOS1 (0.49) ARPGR
SCHEMBL16321481 0.79 AR (0.45) ARPGR
SCHEMBL3040911 0.79 AR (0.54) ARPGR
SCHEMBL5123743 0.78 AR (0.53) ARPGR
SCHEMBL20274218 0.78 JAK3 (0.36) AR
SCHEMBL1240988 0.78 TAS1R3 (0.42) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2922845-B1 ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF MERIAL INC (US) 2018-06-20 EP disclosed