Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | F2 | P00734 | 8/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.55 |
| ▸ | TPSAB1 | Q15661 | 7/20 | 0.54 |
| ▸ | TPSD1 | Q9BZJ3 | 7/20 | 0.54 |
| ▸ | TPSG1 | Q9NRR2 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15750162 | 0.85 | F2 (0.57) | HRH4NPC1RAB9AF2TPSAB1 | |
| SCHEMBL23335840 | 0.81 | PIM1 (0.56) | HRH4NPC1RAB9AF2TPSAB1 | |
| SCHEMBL30578692 | 0.81 | RAB9A (0.74) | HRH4NPC1RAB9ADPP4DPP8 | |
| SCHEMBL30578705 | 0.80 | RAB9A (0.69) | HRH4NPC1RAB9AF2DPP4 | |
| SCHEMBL20274139 | 0.80 | HRH4 (0.47) | HRH4NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL4376465 | 0.79 | RAB9A (0.71) | HRH4NPC1RAB9ADPP4DPP8 | |
| SCHEMBL20274131 | 0.78 | HRH4 (0.48) | HRH4NPC1RAB9AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL4380447 | 0.78 | RAB9A (0.70) | HRH4NPC1RAB9ADPP4DPP8 | |
| SCHEMBL4924339 | 0.76 | NPC1 (0.63) | HRH4NPC1RAB9ADPP4DPP8 | |
| SCHEMBL4917179 | 0.76 | HRH4 (0.68) | HRH4NPC1RAB9ADPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |