Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 4/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033183 | 0.98 | ALDH1A1 (0.47) | ZDHHC20ZDHHC2ALDH1A1FAAHCA12 | |
| SCHEMBL20274387 | 0.88 | ALDH1A1 (0.44) | ZDHHC20ZDHHC2ALDH1A1FAAHTSHR | |
| SCHEMBL24063911 | 0.85 | ZDHHC20 (0.44) | ZDHHC20ZDHHC2ALDH1A1FAAHCA12 | |
| SCHEMBL4300443 | 0.82 | CA12 (0.50) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL4155059 | 0.82 | CA12 (0.50) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL4152693 | 0.82 | CA12 (0.50) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL4148017 | 0.82 | CA12 (0.50) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL4148175 | 0.82 | CA12 (0.50) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL4155142 | 0.82 | CA12 (0.50) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL4155093 | 0.82 | CA12 (0.50) | ZDHHC20ZDHHC2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3335689-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GmbH (DE) | 2018-06-20 | — | — | EP | disclosed |