Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoguanamine SCHEMBL21351508 | 0.91 | TPH1 (0.71) | TPH1SLC7A5 | |
| SCHEMBL837014 | 0.81 | SLC7A5 (0.74) | TPH1SLC7A5 | |
| SCHEMBL156189 | 0.81 | SLC7A5 (0.74) | TPH1SLC7A5 | |
| SCHEMBL309002 | 0.81 | TPH1 (1.00) | TPH1 | |
| SCHEMBL20274857 | 0.80 | TPH1 (0.60) | TPH1 | |
| SCHEMBL12159891 | 0.80 | TPH1 (0.62) | TPH1SLC7A5 | |
| SCHEMBL20274810 | 0.80 | TPH1 (0.59) | TPH1SLC7A5 | |
| SCHEMBL31369650 | 0.79 | SLC7A5 (0.61) | TPH1SLC7A5 | |
| SCHEMBL26966009 | 0.79 | SLC7A5 (0.61) | TPH1SLC7A5 | |
| SCHEMBL25868363 | 0.79 | SLC7A5 (0.66) | TPH1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2386547-B1 | Multicyclic amino acid derivatives and methods of their use | LEXICON PHARMACEUTICALS INC (US) | 2018-06-20 | — | — | EP | disclosed |