SCHEMBL25868363

SCHEMBL25868363

NC(Cc1ccc(-c2nnc(-c3ccccc3)nn2)cc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.66
ALPI P09923 1/20 0.66
PKM P14618 1/20 0.66
PTGS1 P23219 1/20 0.66
XIAP P98170 1/20 0.66
TPH1 P17752 15/20 0.60
SRR Q9GZT4 1/20 0.50
PSAT1 Q9Y617 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL180272 0.88 SLC7A5 (0.78) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL1796036 0.88 SLC7A5 (0.78) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL93494 0.88 SLC7A5 (0.78) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL93495 0.88 SLC7A5 (0.78) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL414363 0.88 SLC7A5 (0.78) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL17044684 0.88 SLC7A5 (0.54) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL16387903 0.88 SLC7A5 (0.54) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL26158250 0.87 SLC7A5 (0.54) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL7567510 0.86 SLC7A5 (0.75) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL3695982 0.86 SLC7A5 (0.75) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116615259-A Uricase-albumin conjugate, preparation method and application thereof ProAb生物技术(股份)有限公司 2023-08-18 CN disclosed
US-20230211002-A1 URATE OXIDASE-ALBUMIN CONJUGATE, PREPARATION METHOD THEREOF, AND USE THEREOF PROABTECH CO., LTD. (KR) 2023-07-06 US disclosed
US-20230211002-A1 URATE OXIDASE-ALBUMIN CONJUGATE, PREPARATION METHOD THEREOF, AND USE THEREOF PROABTECH CO., LTD. (KR) 2023-07-06 US disclosed
US-20230149517-A1 URATE OXIDASE-ALBUMIN CONJUGATE, PREPARATION METHOD THEREOF, AND USE THEREOF PROABTECH CO., LTD. (KR) 2023-05-18 US disclosed
US-20230149517-A1 URATE OXIDASE-ALBUMIN CONJUGATE, PREPARATION METHOD THEREOF, AND USE THEREOF PROABTECH CO., LTD. (KR) 2023-05-18 US disclosed
WO-2022164291-A2 MULTIMERIC PROTEIN-ALBUMIN CONJUGATE, PREPARATION METHOD THEREFOR, AND USE THEREOF 주식회사 프로앱텍 2022-08-04 WO disclosed
WO-2022065936-A1 CONJUGATE OF FUNCTIONAL POLYPEPTIDE VARIANT, AND USE THEREOF 주식회사 프로앱텍 2022-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149517-A1 URATE OXIDASE-ALBUMIN CONJUGATE, PREPARATION METHOD THEREOF, AND USE THEREOF ALB, AOX1, PNPO SLC7A5 3194/4885ALPI 266/4885PKM 3120/4885
US-20230211002-A1 URATE OXIDASE-ALBUMIN CONJUGATE, PREPARATION METHOD THEREOF, AND USE THEREOF ALB, AOX1, PNPO SLC7A5 3194/4885ALPI 266/4885PKM 3120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.