Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20275559 | 0.94 | YTHDC1 (0.38) | YTHDC1TLR7FLT3TLR8 | |
| SCHEMBL3265229 | 0.88 | TLR7 (0.41) | TLR7ADORA3TLR8 | |
| SCHEMBL567026 | 0.88 | TLR7 (0.41) | TLR7ADORA3TLR8 | |
| SCHEMBL19050043 | 0.85 | YTHDC1 (0.44) | YTHDC1TLR7FLT3TLR8 | |
| SCHEMBL2197707 | 0.82 | TLR7 (0.44) | TLR7ADORA3TLR8 | |
| SCHEMBL29697240 | 0.82 | TLR7 (0.44) | TLR7ADORA3TLR8 | |
| SCHEMBL565796 | 0.82 | TLR7 (0.44) | TLR7ADORA3TLR8 | |
| SCHEMBL2195829 | 0.82 | TLR7 (0.44) | TLR7ADORA3TLR8 | |
| SCHEMBL20275530 | 0.81 | YTHDC1 (0.60) | YTHDC1ADORA3FLT3 | |
| SCHEMBL566039 | 0.78 | ADORA2A (0.41) | TLR7ADORA3TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3336089-A1 | PURINE DERIVATIVES FOR USE IN THE TREATMENT OF ALLERGIC, INFLAMMATORY AND INFECTIOUS DISEASES | GlaxoSmithKline LLC (US) | 2018-06-20 | — | — | EP | disclosed |