Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | LIPE | Q05469 | 6/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31440036 | 0.88 | LPL (0.39) | LPLLIPGJAK2BTKLIPE | |
| SCHEMBL4879042 | 0.88 | LPL (0.39) | LPLLIPGJAK2BTKLIPE | |
| SCHEMBL17334100 | 0.84 | LPL (0.42) | LPLLIPGJAK2BTKLIPE | |
| SCHEMBL24630498 | 0.84 | LPL (0.46) | LPLLIPGJAK2BTK | |
| SCHEMBL2301628 | 0.79 | JAK2 (0.43) | LPLLIPGJAK2BTK | |
| SCHEMBL13601620 | 0.77 | LPL (0.41) | LPLLIPGJAK2BTK | |
| SCHEMBL31419590 | 0.77 | LIPE (0.34) | LPLLIPGJAK2BTKLIPE | |
| SCHEMBL4872385 | 0.76 | MPL (0.39) | LPLLIPGJAK2BTKLIPE | |
| SCHEMBL1478043 | 0.76 | LPL (0.40) | LPLLIPGLIPEF2F11 | |
| SCHEMBL29556711 | 0.76 | LPL (0.40) | LPLLIPGLIPEF2F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076687-A1 | PYRIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-06-30 | — | — | WO | disclosed |
| WO-2011076687-A1 | PYRIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-06-30 | — | — | WO | disclosed |