SCHEMBL20277263

SCHEMBL20277263

CC1(C)c2cc(-c3ccccc3)ccc2-c2ccc(-c3ccc4oc5ccccc5c4c3)cc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 5/20 0.46
PLA2G4A P47712 5/20 0.46
NPC1 O15118 2/20 0.41
HPGD P15428 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
PLA2G10 O15496 1/20 0.41
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
PGR P06401 2/20 0.39
PDK2 Q15119 1/20 0.38
MAOA P21397 1/20 0.38
AHR P35869 1/20 0.38
PRKDC P78527 2/20 0.38
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16788582 0.97 PLA2G2A (0.44) PLA2G2APLA2G4ANPC1HPGDRAB9A
SCHEMBL13443626 0.97 MAPT (0.44) PLA2G2APLA2G4ANPC1HPGDRAB9A
SCHEMBL1637407 0.93 PLA2G2A (0.41) PLA2G2APLA2G4AKDM4EMEN1ALDH1A1
SCHEMBL1637658 0.91 PRKDC (0.40) PLA2G2APLA2G4AKDM4EMEN1ALDH1A1
SCHEMBL1636090 0.91 PLA2G2A (0.40) PLA2G2APLA2G4ANPC1HPGDRAB9A
SCHEMBL18086158 0.91 HSP90AA1 (0.43) PLA2G2APLA2G4ANPC1HPGDRAB9A
SCHEMBL16017880 0.91 HSP90AA1 (0.43) PLA2G2APLA2G4ANPC1HPGDRAB9A
SCHEMBL1635433 0.91 PLA2G2A (0.40) PLA2G2APLA2G4ANPC1HPGDRAB9A
SCHEMBL9916304 0.91 PLA2G2A (0.40) PLA2G2APLA2G4ANPC1HPGDRAB9A
SCHEMBL12694849 0.91 PLA2G2A (0.40) PLA2G2APLA2G4ANPC1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11358951-B2 Π(PI)-conjugated compound, organic electroluminescence element material, light-emitting material, light-emitting thin film, organic electroluminescence element, display device, and illumination device MERCK PATENT GMBH (DE) 2022-06-14 US disclosed
US-20180170914-A1 II(PI)-CONJUGATED COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, LIGHT-EMITTING MATERIAL, LIGHT-EMITTING THIN FILM, ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, AND ILLUMINATION DEVICE Konica Minolta, Inc. (JP) 2018-06-21 US disclosed
US-20180170914-A1 II(PI)-CONJUGATED COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, LIGHT-EMITTING MATERIAL, LIGHT-EMITTING THIN FILM, ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, AND ILLUMINATION DEVICE Konica Minolta, Inc. (JP) 2018-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180170914-A1 II(PI)-CONJUGATED COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, LIGHT-EMITTING MATERIAL, LIGHT-EMITTING THIN FILM, ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, AND ILLUMINATION DEVICE OCIAD2, ZYX, OCIAD1 PLA2G2A 3008/4885PLA2G4A 3778/4885NPC1 2021/4885
US-11358951-B2 Π(PI)-conjugated compound, organic electroluminescence element material, light-emitting material, light-emitting thin film, organic electroluminescence element, display device, and illumination device ZYX, OCIAD2, DRD1 PLA2G2A 3541/4885PLA2G4A 4083/4885NPC1 1688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.