SCHEMBL1637407

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1637658	0.96	PRKDC (0.40)	PLA2G2APLA2G4APDK2PGRPRKDC
	SCHEMBL1635433	0.96	PLA2G2A (0.40)	PLA2G2APLA2G4APDK2PGRPRKDC
	SCHEMBL1635653	0.94	PLA2G2A (0.39)	PLA2G2APLA2G4APDK2PGRPRKDC
	SCHEMBL1636090	0.93	PLA2G2A (0.40)	PLA2G2APLA2G4APDK2PGRPRKDC
	SCHEMBL20277263	0.93	PLA2G2A (0.46)	PLA2G2APLA2G4APDK2PGRPRKDC
	SCHEMBL1637406	0.91	PDK2 (0.37)	PLA2G2APLA2G4APDK2PGRHSP90AA1
	SCHEMBL1636522	0.91	PDK2 (0.39)	PDK2PGRPRKDCGAAL3MBTL1
	SCHEMBL16788582	0.90	PLA2G2A (0.44)	PLA2G2APLA2G4APDK2PGRPRKDC
	SCHEMBL1636888	0.90	PLA2G2A (0.40)	PLA2G2APLA2G4APDK2PGRPRKDC
	SCHEMBL13443626	0.90	MAPT (0.44)	PLA2G2APLA2G4APGRPLA2G10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.