SCHEMBL2027845

SCHEMBL2027845

c1ccc(CC2CCC(Cc3ccccc3)CC2)cc1

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ GBA1 P04062 1/20 0.71
▸ CCR3 P51677 3/20 0.63
▸ PRMT3 O60678 1/20 0.57
▸ CARM1 Q86X55 1/20 0.57
▸ PRMT6 Q96LA8 1/20 0.57
▸ PRMT1 Q99873 1/20 0.57
▸ PRMT8 Q9NR22 1/20 0.57
▸ GRIN2B Q13224 2/20 0.55
▸ MGLL Q99685 1/20 0.55
▸ SIGMAR1 Q99720 2/20 0.53
▸ ALDH1A1 P00352 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL674276 1.00 GBA1 (0.71) GBA1CCR3PRMT3CARM1PRMT6
Ammonia Solution, Strong SCHEMBL1432566 0.97 GBA1 (0.68) GBA1CCR3PRMT3CARM1PRMT6
Hydrochloric Acid SCHEMBL4797146 0.95 GBA1 (0.65) GBA1CCR3PRMT3CARM1PRMT6
SCHEMBL8701 0.90 GBA1 (0.65) GBA1CCR3PRMT3CARM1PRMT6
SCHEMBL316482 0.90 GBA1 (0.65) GBA1CCR3PRMT3CARM1PRMT6
SCHEMBL8414688 0.89 GBA1 (0.59) GBA1CCR3PRMT3CARM1PRMT6
SCHEMBL8595149 0.89 GBA1 (0.59) GBA1CCR3PRMT3CARM1PRMT6
SCHEMBL14327146 0.89 GBA1 (0.59) GBA1CCR3PRMT3CARM1PRMT6
SCHEMBL10523879 0.89 GBA1 (0.59) GBA1CCR3PRMT3CARM1PRMT6
SCHEMBL595262 0.89 GBA1 (0.59) GBA1CCR3PRMT3CARM1PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10457621-B2 Process for preparing aryl ketone ETERNAL MATERIALS CO., LTD. (TW) 2019-10-29 — — US disclosed
US-20170036981-A1 PROCESS FOR PREPARING ARYL KETONE ETERNAL MATERIALS CO., LTD. (TW) 2017-02-09 — — US disclosed
US-7956528-B2 Organic electroluminescent device comprising ceramic sheet and graphite sheet FUJIFILM CORPORATION (JP) 2011-06-07 — — US disclosed
CN-1899815-B Gas barrier film, substrate film, and organic electroluminescence device FUJI PHOTO FILM CO LTD 2010-05-12 — — CN disclosed
CN-1899815-A Gas barrier film, substrate film, and organic electroluminescence device FUJI PHOTO FILM CO LTD (JP) 2007-01-24 — — CN disclosed
US-20060207649-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. 2006-09-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10457621-B2 Process for preparing aryl ketone CYP1B1, CYP4X1, PKM GBA1 1456/4885CCR3 2985/4885PRMT3 3241/4885
US-20170036981-A1 PROCESS FOR PREPARING ARYL KETONE CYP1B1, CYP4X1, PKM GBA1 1456/4885CCR3 2985/4885PRMT3 3241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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