SCHEMBL595262

SCHEMBL595262

[CH2]C1CCC(Cc2ccccc2)CC1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GBA1 P04062 1/20 0.59
▸ CCR3 P51677 2/20 0.53
▸ PRMT3 O60678 1/20 0.49
▸ CARM1 Q86X55 1/20 0.49
▸ PRMT6 Q96LA8 1/20 0.49
▸ PRMT1 Q99873 1/20 0.49
▸ PRMT8 Q9NR22 1/20 0.49
▸ GRIN2B Q13224 1/20 0.47
▸ MGLL Q99685 1/20 0.47
▸ KMT2A Q03164 1/20 0.46
▸ FAAH O00519 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ SIGMAR1 Q99720 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL674276 0.89 GBA1 (0.71) GBA1CCR3PRMT3CARM1PRMT6
SCHEMBL2027845 0.89 GBA1 (0.71) GBA1CCR3PRMT3CARM1PRMT6
Ammonia Solution, Strong SCHEMBL1432566 0.86 GBA1 (0.68) GBA1CCR3PRMT3CARM1PRMT6
Hydrochloric Acid SCHEMBL4797146 0.84 GBA1 (0.65) GBA1CCR3PRMT3CARM1PRMT6
SCHEMBL8701 0.79 GBA1 (0.65) GBA1CCR3PRMT3CARM1PRMT6
SCHEMBL316482 0.79 GBA1 (0.65) GBA1CCR3PRMT3CARM1PRMT6
SCHEMBL8595149 0.78 GBA1 (0.59) GBA1CCR3PRMT3CARM1PRMT6
SCHEMBL8414688 0.78 GBA1 (0.59) GBA1CCR3PRMT3CARM1PRMT6
SCHEMBL5525779 0.78 GBA1 (0.59) GBA1CCR3PRMT3CARM1PRMT6
SCHEMBL10523879 0.78 GBA1 (0.59) GBA1CCR3PRMT3CARM1PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1014 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4818748-A HYPOTENSIVE AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1989-04-04 — — US claimed
EP-0236874-A2 Renin inhibitors, their production and use, as well as derivatives of amino acids and amino aldehydes BAYER AG (DE) 1987-09-16 — — EP claimed
US-12043573-B2 Adhesion promoters and gel-modifiers for olefin metathesis compositions MATERIA, INC. (US) 2024-07-23 — — US disclosed
EP-3386936-B1 OLEFIN METATHESIS CATALYSTS UMICORE AG & CO KG (DE) 2024-07-10 — — EP disclosed
CN-118317986-A Hydrophobically modified and hydrophilically modified maleated natural oils, salts, compositions and methods of use 埃斯普投资有限公司 2024-07-09 — — CN disclosed
CN-118302488-A Hydrophobically modified and hydrophilically modified maleated natural oils and compositions thereof 埃斯普投资有限公司 2024-07-05 — — CN disclosed
CN-113423549-B Coating composition 马特里亚公司 2024-06-25 — — CN disclosed
CN-118235086-A Radiation-sensitive composition comprising a combination of metals or metalloid compounds 埃斯普投资有限公司 2024-06-21 — — CN disclosed
EP-3016991-B1 LIQUID MOLDING COMPOSITIONS MATERIA INC (US) 2024-06-12 — — EP disclosed
US-20240174688-A1 COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2024-05-30 — — US disclosed
CN-118059093-A Inhibitors of short chain dehydrogenase activity for the treatment of fibrosis 卡斯西部储备大学 2024-05-24 — — CN disclosed
US-20020042365-A1 Vancomycin analogs TRUSTEES OF PRINCETON UNIVERSITY, THE 2002-04-11 — — US disclosed
EP-1173193-A1 DESLEUCYL GLYCOPEPTIDE ANTIBIOTICS AND METHODS OF MAKING SAME The Trustees of Princeton University (US) 2002-01-23 — — EP disclosed
CN-1071334-C Glycopeptide antibiotic derivatives LILLY CO ELI (US) 2001-09-19 — — CN disclosed
WO-2000059528-A1 DESLEUCYL GLYCOPEPTIDE ANTIBIOTICS AND METHODS OF MAKING SAME THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2000-10-12 — — WO disclosed
EP-1016670-A1 Glycopeptide antibiotic derivatives ELI LILLY AND COMPANY (US) 2000-07-05 — — EP disclosed
US-5977062-A ACTIVE AGAINST ANTIBIOTIC RESISTANT BACTERIA ELI LILLY AND COMPANY (US) 1999-11-02 — — US disclosed
CN-1119649-A Glycopeptide antibiotic derivatives LILLY CO ELI (US) 1996-04-03 — — CN disclosed
US-4818748-A HYPOTENSIVE AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1989-04-04 — — US disclosed
EP-0236874-A2 Renin inhibitors, their production and use, as well as derivatives of amino acids and amino aldehydes BAYER AG (DE) 1987-09-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174688-A1 COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY HPGD, GCDH, HPGDS GBA1 946/4885CCR3 4569/4885PRMT3 2786/4885
US-20020042365-A1 Vancomycin analogs VNN1, PTMS, ASNS GBA1 2232/4885CCR3 151/4885PRMT3 1266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback