Desciclovir

Desciclovir

SCHEMBL2028

Nc1ncc2ncn(COCCO)c2n1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNP P00491 7/20 0.52
HSD17B10 Q99714 2/20 0.52
USP2 O75604 1/20 0.52
TSHR P16473 1/20 0.52
EDNRA P25101 1/20 0.52
HTR2A P28223 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
HBB P68871 1/20 0.52
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
ADRA1A P35348 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
HDAC6 Q9UBN7 2/20 0.45
HSP90AA1 P07900 1/20 0.44
HSP90AB1 P08238 1/20 0.44
HPRT1 P00492 3/20 0.39
ENPP1 P22413 1/20 0.36
POLG P54098 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Desciclovir SCHEMBL29403096 1.00 PNP (0.52) PNPHSD17B10USP2TSHREDNRA
SCHEMBL11001378 0.92 HSD17B10 (0.46) PNPHSD17B10USP2TSHREDNRA
Desciclovir SCHEMBL28719436 0.90 PNP (0.50) PNPHSD17B10USP2TSHREDNRA
SCHEMBL8933938 0.87 HSD17B10 (0.52) PNPHSD17B10USP2TSHREDNRA
SCHEMBL10650936 0.87 HSD17B10 (0.45) PNPHSD17B10USP2TSHREDNRA
SCHEMBL4255333 0.82 HSD17B10 (0.49) PNPHSD17B10USP2TSHREDNRA
SCHEMBL8926305 0.82 HSD17B10 (0.61) PNPHSD17B10USP2TSHREDNRA
SCHEMBL10528638 0.81 HSD17B10 (0.49) PNPHSD17B10USP2TSHREDNRA
SCHEMBL3151968 0.80 KDM4E (0.55) HSD17B10KDM4EALDH1A1HPGDADRA1A
SCHEMBL10997155 0.79 HDAC6 (0.43) HSD17B10TSHRKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1915 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
WO-2026043843-A1 TETRAHYDROPYRIMIDINE (THP) IONIZABLE LIPIDS FOR EFFICIENT MRNA DELIVERY THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, (US) 2026-02-26 WO claimed
WO-2025076059-A1 ROCAGLATE DERIVATIVES AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2025-04-10 WO claimed
WO-2025034898-A1 GASTRIC CANCER PATIENT CLASSIFICATION AND METHODS OF TREATMENT BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-02-13 WO claimed
WO-2024215771-A1 SUBSTITUTED PHENYL ETHYNYL PYRIMIDINES AS POTENT INHIBITORS OF ALPHAVIRUSES SOUTHERN RESEARCH INSTITUTE (US) 2024-10-17 WO claimed
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2024-05-02 US claimed
EP-4262812-A1 6-AZA-NUCLEOSIDE PRODRUGS AS ANTIVIRAL AGENTS FOR TREATING VIRUS INFECTIONS Southern Research Institute (US) 2023-10-25 EP claimed
WO-2023122212-A2 SUBSTITUTED PHENYL ETHYNYL PYRIDINE CARBOXAMIDES AS POTENT INHIBITORS OF SARS VIRUS SOUTHERN RESEARCH INSTITUTE (US) 2023-06-29 WO claimed
CN-115916175-A Novel 2-pyrimidinone analogs as potent antiviral agents against alphaviruses 南方研究院 2023-04-04 CN claimed
EP-4125845-A1 NOVEL 2-PYRIMIDONE ANALOGS AS POTENT ANTIVIRAL AGENTS AGAINST ALPHAVIRUSES Southern Research Institute (US) 2023-02-08 EP claimed
EP-0235931-B1 ANTIVIRAL COMBINATION THE WELLCOME FOUNDATION LIMITED (GB) 1990-07-11 EP claimed
EP-0158847-B1 ANTIVIRAL PURINE DERIVATIVES THE WELLCOME FOUNDATION LIMITED (GB) 1988-04-20 EP claimed
EP-0108285-B1 ANTIVIRAL PURINE DERIVATIVES THE WELLCOME FOUNDATION LIMITED (GB) 1988-04-20 EP claimed
EP-0235931-A1 Antiviral combination THE WELLCOME FOUNDATION LIMITED (GB) 1987-09-09 EP claimed
EP-0217580-A2 Therapeutic nucleosides THE WELLCOME FOUNDATION LIMITED (GB) 1987-04-08 EP claimed
US-4649140-A 6-DEOXYACYCLOVIR, VIRICIDES BURROUGHS WELLCOME CO. (US) 1987-03-10 US claimed
EP-0158847-A1 Antiviral purine derivatives THE WELLCOME FOUNDATION LIMITED (GB) 1985-10-23 EP claimed
EP-0158513-A2 Antiviral compounds THE WELLCOME FOUNDATION LIMITED (GB) 1985-10-16 EP claimed
EP-0135713-A2 Antiviral combinations THE WELLCOME FOUNDATION LIMITED (GB) 1985-04-03 EP claimed
EP-0108285-A2 Antiviral purine derivatives THE WELLCOME FOUNDATION LIMITED (GB) 1984-05-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS HAVCR2, NR1H4, NR1H3 PNP 1440/4885HSD17B10 235/4885USP2 4142/4885
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS SLC10A1, HAVCR2, HDGF PNP 706/4885HSD17B10 125/4885USP2 4444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.