Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | TK1 | P04183 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933938 | 0.85 | HSD17B10 (0.52) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL6307469 | 0.84 | KDM4E (0.57) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL3157542 | 0.83 | HSD17B10 (0.52) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL14010824 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9116846 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| 6-Deoxy Penciclovir SCHEMBL660970 | 0.83 | ALDH1A1 (0.66) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| 6-Deoxy Penciclovir SCHEMBL29797811 | 0.83 | ALDH1A1 (0.66) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL10711562 | 0.83 | KDM4E (0.62) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9117042 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| 6-Deoxy Penciclovir SCHEMBL3324010 | 0.82 | ALDH1A1 (0.65) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101555249-B | Method for synthesizing famciclovir | ZHEJIANG HISUN PHARM CO LTD | 2011-05-11 | — | — | CN | disclosed |
| EP-1883639-B1 | PREPARATION OF FAMCICLOVIR AND OTHER PURINE DERIVATIVES | ARROW INT LTD (MT) | 2010-09-01 | — | — | EP | disclosed |
| EP-1636231-B1 | METHODS FOR PREPARING 9-[4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]-2-AMINOPURINE USING A COMPOUND OF 2-AMINO-9-(2-SUBSTITUTED ETHYL)PURINES | KYUNGDONG PHARM CO LTD (KR) | 2010-03-24 | — | — | EP | disclosed |
| EP-1636231-B1 | METHODS FOR PREPARING 9-[4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]-2-AMINOPURINE USING A COMPOUND OF 2-AMINO-9-(2-SUBSTITUTED ETHYL)PURINES | KYUNGDONG PHARM CO LTD (KR) | 2010-03-24 | — | — | EP | disclosed |
| CN-101555249-A | Method for synthesizing famciclovir | ZHEJIANG HISUN PHARMACEUTICAL (CN) | 2009-10-14 | — | — | CN | disclosed |
| US-7601835-B2 | Preparation of famciclovir and other purine derivatives | ARROW INTERNATIONAL LIMITED (MT) | 2009-10-13 | — | — | US | disclosed |
| US-7601835-B2 | Preparation of famciclovir and other purine derivatives | ARROW INTERNATIONAL LIMITED (MT) | 2009-10-13 | — | — | US | disclosed |
| CN-100455583-C | 2-amino-9- (2-substituted ethyl) purines and methods of using same to prepare 9- [ 4-acetoxy-3- (acetoxymethyl) butan-1-yl ] -2-aminopurine | KYUNGDONG PHARM CO LTD (KR) | 2009-01-28 | — | — | CN | disclosed |
| US-7456282-B2 | 2-amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same | KYUNGDONG PHARM. CO., LTD. (KR) | 2008-11-25 | — | — | US | disclosed |
| US-7456282-B2 | 2-amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same | KYUNGDONG PHARM. CO., LTD. (KR) | 2008-11-25 | — | — | US | disclosed |
| US-7456282-B2 | 2-amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same | KYUNGDONG PHARM. CO., LTD. (KR) | 2008-11-25 | — | — | US | disclosed |
| US-20060258862-A1 | 2-Amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same | KYUNGDONG PHARM. CO., LTD. (KR) | 2006-11-16 | — | — | US | disclosed |
| CN-1791602-A | 2-amino-9-(2-substituted ethyl)purines and preparing methods for 9- 4-acetoxy-3-(acetoxymethyl)but-1-yl]- 2- aminopurine using the same | KYUNGDONG PHARM CO LTD (KR) | 2006-06-21 | — | — | CN | disclosed |
| EP-1636231-A2 | 2-AMINO-9-(2-SUBSTITUTED ETHYL)PURINES AND PREPARING METHODS FOR 9- 4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]- 2- AMINOPURINE USING THE SAME | Kyungdong Pharm. Co., Ltd. (KR) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110343-A2 | 2-AMINO-9-(2-SUBSTITUTED ETHYL)PURINES AND PREPARING METHODS FOR 9-[4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]- 2- AMINOPURINE USING THE SAME | KYUNGDONG PHARM. CO., LTD. (KR) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258862-A1 | 2-Amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same | TYMP, TPMT, PNP | KDM4E 783/4885ALDH1A1 1015/4885HPGD 2021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.