SCHEMBL20280290

SCHEMBL20280290

CCC1CN(CCC(C)C)C1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.34
SORT1 Q99523 1/20 0.31
GLB1 P16278 1/20 0.30
PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21660212 0.83 CARM1 (0.34) PIK3CD
SCHEMBL18389282 0.80 ARG1 (0.37)
SCHEMBL18082542 0.80 BCHE (0.42)
SCHEMBL10076884 0.80 BCHE (0.42)
SCHEMBL10150975 0.78 PIK3CD (0.50) PIK3CD
SCHEMBL17681022 0.77
SCHEMBL12280928 0.77 GBA1 (0.30) GBA1
SCHEMBL27013138 0.76 GBA1 (0.34) GBA1SORT1GLB1PIK3CD
SCHEMBL13171586 0.75 GBA1 (0.40) GBA1SORT1PIK3CD
SCHEMBL25445185 0.73 SIGMAR1 (0.41) GBA1SORT1PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10550071-B2 PPAR agonists SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2020-02-04 US disclosed
WO-2019031618-A1 PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE 大正製薬株式会社 2019-02-14 WO disclosed
EP-3434668-A1 INDOLO-SUBSTITUTED-PIPERIDINE COMPOUNDS AS ESTROGEN RECEPTOR DEGRADING AGENT Luoxin Biotechnology (Shanghai) Co., Ltd. (CN) 2019-01-30 EP disclosed
US-20180170857-A1 PPAR AGONISTS SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2018-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180170857-A1 PPAR AGONISTS PPARG, PPARD, PPARA GBA1 1690/4885SORT1 4360/4885GLB1 1573/4885
US-10550071-B2 PPAR agonists PPARG, PPARD, PPARA GBA1 1690/4885SORT1 4360/4885GLB1 1573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.