Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | CASP1 | P29466 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19471306 | 0.89 | ALDH1A1 (0.62) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL49805 | 0.85 | ALDH1A1 (1.00) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL17845262 | 0.83 | ALDH1A1 (0.78) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL48404 | 0.83 | ALDH1A1 (0.78) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| Ammonia Solution, Strong SCHEMBL10393256 | 0.82 | ALDH1A1 (0.75) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL22133453 | 0.81 | TDP1 (0.50) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL24684892 | 0.80 | ALDH1A1 (0.72) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL27905916 | 0.79 | CYP3A4 (0.64) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL249357 | 0.79 | L3MBTL1 (0.78) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL11482583 | 0.79 | ALDH1A1 (0.86) | ALDH1A1CYP3A4ALOX15TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-11420934-B2 | PPAR agonists | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2022-08-23 | — | — | US | disclosed |
| US-20200190019-A1 | PPAR AGONISTS | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2020-06-18 | — | — | US | disclosed |
| US-10550071-B2 | PPAR agonists | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2020-02-04 | — | — | US | disclosed |
| US-20180170857-A1 | PPAR AGONISTS | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2018-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11420934-B2 | PPAR agonists | PPARG, PPARD, PPARA | ALDH1A1 1664/4885CYP3A4 2641/4885ALOX15 915/4885 |
| US-20180170857-A1 | PPAR AGONISTS | PPARG, PPARD, PPARA | ALDH1A1 1664/4885CYP3A4 2641/4885ALOX15 915/4885 |
| US-20200190019-A1 | PPAR AGONISTS | PPARG, PPARD, PPARA | ALDH1A1 1664/4885CYP3A4 2641/4885ALOX15 915/4885 |
| US-10550071-B2 | PPAR agonists | PPARG, PPARD, PPARA | ALDH1A1 1664/4885CYP3A4 2641/4885ALOX15 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.