Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.68 |
| ▸ | CCR6 | P51684 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | TDO2 | P48775 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728387 | 0.81 | L3MBTL1 (1.00) | L3MBTL1HSP90AA1CCR6KMT2AMAPT | |
| SCHEMBL5728388 | 0.81 | L3MBTL1 (1.00) | L3MBTL1HSP90AA1CCR6KMT2AMAPT | |
| SCHEMBL27589733 | 0.78 | L3MBTL1 (0.69) | L3MBTL1HSP90AA1CCR6KMT2AMAPT | |
| SCHEMBL20280307 | 0.78 | L3MBTL1 (0.69) | L3MBTL1HSP90AA1CCR6KMT2AMAPT | |
| SCHEMBL20280046 | 0.78 | L3MBTL1 (0.69) | L3MBTL1HSP90AA1CCR6KMT2AMAPT | |
| SCHEMBL20280358 | 0.78 | L3MBTL1 (0.68) | L3MBTL1HSP90AA1CCR6KMT2AMAPT | |
| SCHEMBL18645426 | 0.78 | L3MBTL1 (0.68) | L3MBTL1HSP90AA1CCR6KMT2AMAPT | |
| SCHEMBL20280490 | 0.78 | L3MBTL1 (0.68) | L3MBTL1HSP90AA1CCR6KMT2AMAPT | |
| SCHEMBL11475446 | 0.78 | L3MBTL1 (0.68) | L3MBTL1HSP90AA1CCR6KMT2AMAPT | |
| SCHEMBL13994757 | 0.75 | ALDH1A1 (0.41) | L3MBTL1HSP90AA1CCR6KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3347001-B1 | AZOPHENOLS AS ERG ONCOGENE INHIBITORS | HENRY M JACKSON FOUND ADVANCEMENT MILITARY MEDICINE INC (US) | 2023-07-26 | — | — | EP | disclosed |
| US-10238639-B2 | Azophenols as ERG oncogene inhibitors | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2019-03-26 | — | — | US | disclosed |
| US-20180169074-A1 | Azophenols as ERG Oncogene Inhibitors | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2018-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180169074-A1 | Azophenols as ERG Oncogene Inhibitors | ERG, ESR1, CBX2 | L3MBTL1 2210/4885HSP90AA1 4047/4885CCR6 3626/4885 |
| US-10238639-B2 | Azophenols as ERG oncogene inhibitors | ERG, ESR1, CBX2 | L3MBTL1 2210/4885HSP90AA1 4047/4885CCR6 3626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.