Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | RAD52 | P43351 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23260498 | 0.89 | EHMT2 (0.62) | TP53MAPTPOLBBLM | |
| SCHEMBL30526270 | 0.89 | TP53 (0.56) | TP53MAPTPOLBBLMRAD52 | |
| SCHEMBL10837757 | 0.89 | TP53 (0.56) | TP53MAPTPOLBBLMRAD52 | |
| SCHEMBL8758459 | 0.84 | NPY1R (0.56) | TP53MAPTPOLBBLM | |
| SCHEMBL13901840 | 0.80 | TP53 (0.63) | TP53MAPTPOLBBLMRAD52 | |
| SCHEMBL14564131 | 0.79 | KDM1A (0.58) | POLBKMT2A | |
| SCHEMBL26530734 | 0.78 | EHMT2 (0.67) | — | |
| SCHEMBL6785331 | 0.76 | TP53 (0.52) | TP53MAPTPOLBBLMMEN1 | |
| SCHEMBL6781777 | 0.75 | TP53 (0.50) | TP53MAPTPOLBBLMMEN1 | |
| SCHEMBL8757881 | 0.75 | TP53 (0.48) | TP53MAPTPOLBBLMRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018107200-A1 | HEPARANASE INHIBITORS AND USE THEREOF | Beta Therapeutics Pty Ltd (AU) | 2018-06-21 | — | — | WO | disclosed |