Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6781777 | 0.94 | TP53 (0.50) | TP53MAPTMEN1KMT2AMITF | |
| SCHEMBL8930316 | 0.83 | ABCB1 (0.44) | TP53MAPTMEN1KMT2AABCB1 | |
| SCHEMBL6779380 | 0.81 | KDM1A (0.51) | TP53MAPTMEN1KMT2A | |
| SCHEMBL6779429 | 0.81 | GLA (0.54) | KMT2APOLB | |
| SCHEMBL20280946 | 0.76 | TP53 (0.56) | TP53MAPTMEN1KMT2AMITF | |
| SCHEMBL10837757 | 0.76 | TP53 (0.56) | TP53MAPTMEN1KMT2AMITF | |
| SCHEMBL30526270 | 0.76 | TP53 (0.56) | TP53MAPTMEN1KMT2AMITF | |
| SCHEMBL20280937 | 0.76 | HIF1A (0.46) | TP53MAPTMEN1KMT2A | |
| SCHEMBL20281057 | 0.76 | POLB (0.57) | MAPTMEN1KMT2APOLB | |
| SCHEMBL20280939 | 0.75 | HDAC3 (0.42) | TP53MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8208626-A | — | — | None | — | — | JP | disclosed |
| US-6706705-B1 | SLOW AND CONTINUOUS BLOOD PRESSURE REDUCING ACTION AND IS USEFUL AS AN ANTIHYPERTENSIVE AGENT | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-03-16 | — | — | US | disclosed |
| EP-0794178-A1 | QUINAZOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-09-10 | — | — | EP | disclosed |
| JP-H08208626-A | QUINAZOLINE DERIVATIVE AND HYPOTENSOR | NIPPON CHEMIPHAR CO LTD | 1996-08-13 | — | — | JP | disclosed |