Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 10/20 | 0.67 |
| ▸ | EHMT1 | Q9H9B1 | 7/20 | 0.67 |
| ▸ | KDM1A | O60341 | 5/20 | 0.57 |
| ▸ | RCOR1 | Q9UKL0 | 5/20 | 0.57 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | PDE5A | O76074 | 1/20 | 0.53 |
| ▸ | KMT5A | Q9NQR1 | 4/20 | 0.51 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23260581 | 0.97 | EHMT2 (0.69) | EHMT2EHMT1KDM1ARCOR1KMT5A | |
| SCHEMBL23261467 | 0.96 | EHMT2 (0.68) | EHMT2EHMT1KDM1ARCOR1KMT5A | |
| SCHEMBL23260506 | 0.92 | EHMT2 (0.63) | EHMT2EHMT1KDM1ARCOR1PDE5A | |
| SCHEMBL23260512 | 0.90 | HTT (0.62) | EHMT2EHMT1KDM1ARCOR1PDE5A | |
| SCHEMBL23260582 | 0.85 | EHMT2 (0.54) | EHMT2EHMT1KMT5A | |
| SCHEMBL20620834 | 0.84 | EHMT2 (0.81) | EHMT2EHMT1KDM1ARCOR1HDAC1 | |
| SCHEMBL17122655 | 0.84 | HTT (0.70) | EHMT2EHMT1APPKMT5A | |
| SCHEMBL23260498 | 0.84 | EHMT2 (0.62) | EHMT2EHMT1KDM1ARCOR1 | |
| SCHEMBL23260504 | 0.82 | BRD4 (0.54) | EHMT2EHMT1KDM1ARCOR1KMT5A | |
| SCHEMBL13975836 | 0.82 | TLR7 (0.53) | EHMT2EHMT1APPKMT5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | YTHDF1, YTHDF3, YTHDF2 | EHMT2 231/4885EHMT1 296/4885KDM1A 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.