Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20280937 | 0.79 | HIF1A (0.46) | TP53MAPTMEN1KMT2A | |
| SCHEMBL20281113 | 0.77 | TP53 (0.50) | TP53MAPTMEN1KMT2APOLB | |
| SCHEMBL20281121 | 0.75 | ADRA2A (0.40) | — | |
| SCHEMBL20281124 | 0.75 | ADRA2A (0.38) | — | |
| SCHEMBL6785331 | 0.75 | TP53 (0.52) | TP53MAPTMEN1KMT2APOLB | |
| SCHEMBL20280954 | 0.74 | TLR8 (0.40) | TP53MAPTMEN1KMT2A | |
| SCHEMBL20281112 | 0.73 | CDK2 (0.42) | TP53MAPTMEN1KMT2A | |
| SCHEMBL20281057 | 0.70 | POLB (0.57) | MAPTMEN1KMT2APOLB | |
| SCHEMBL20280939 | 0.70 | HDAC3 (0.42) | TP53MAPTMEN1KMT2A | |
| SCHEMBL6781777 | 0.69 | TP53 (0.50) | TP53MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018107200-A1 | HEPARANASE INHIBITORS AND USE THEREOF | Beta Therapeutics Pty Ltd (AU) | 2018-06-21 | — | — | WO | disclosed |